Henry Gray (18251861). Anatomy of the Human Body. 1918.
interior the cells or osteoblasts predominate; the whole tissue is richly supplied with blood vessels. At the outset of the process of bone formation a little network of spicules is noticed radiating from the point or center of ossification. These rays consist at their growing points of a network of fine clear fibers and granular corpuscles with an intervening ground substance (Fig. 78). The fibers are termed osteogenetic fibers, and are made up of fine fibrils differing little from those of white fibrous tissue. The membrane soon assumes a dark and granular appearance from the deposition of calcareous granules in the fibers and in the intervening matrix, and in the calcified material some of the granular corpuscles or osteoblasts are enclosed. By the fusion of the calcareous granules the tissue again assumes a more transparent appearance, but the fibers are no longer so distinctly seen. The involved osteoblasts from the corpuscles of the future bone, the spaces in