Aim and Introduction Recurrent aphthous ulceration (RAU) is the most common oral mucosal disorder, affecting 20% of the general population (see figure 1)(Akintoye and Greenberg 1997). RAU is classified into 3 subtypes with minor RAU being the most prevalent form (Barrons 2001). Due to its unknown etiology, there is no effective method in terminating its outbreaks, though the symptoms can currently be relieved through topical treatments (Femiano et al 2007). RAU is an issue of concern for dentists, as it negatively impacts patients ' quality of life, by impeding eating, swallowing, and speaking (Baharvad 2014). Therefore, there is strong interest for researchers to find new agents to potentially treat RAU. This paper aims to critically …show more content…
Small sample sizes were used in all of the studies, making the results questionable, if applied to the general population. Also, there were no power calculations made, except in (Lui et al 2012). Although the selection criterion removed potential confounding factors, they narrowed down the applicability of the findings. This included exclusion of proposed etiological factors for RAU, such as Behcet’s, Chrohn’s and ulcerative colitis. All 5 studies analysed changes in ulcer size and pain between each treatment and control group. However, pain is subjective between individuals and hard to localise to one ulcer, thus making it a difficult variable to compare. Dexamethasone Dexamethasone is a topical steroid. Its anti-inflammatory and immunosuppressive qualities led to a systematic review that revealed a decrease in ulcer duration, in comparison to the placebo (Quijano and Rodriquez, 2008). (Lui et al 2012) were the first to look into systemic safety concerns in the use of topical dexamethasone treatment in MiRAU by measuring serum concentration of dexamethasone. This means that there was a lack of previous evidence to support their findings. Only 89/240 subjects from 2/5 centers were chosen for the safety analysis, along with no power calculation to determine the subsample size (Lui et al 2012). This further questions the reliability of their results. Smokers were removed from
The aim of this article was to assess the validity of the Waterlow Scale instrument using a longitudinal cohort of internal medical patients. To identify risk factors contributing to the injury of pressure ulcers (information outlined in the abstract overview of the study) (BJN, 2010).
Also victimized by Youth Research are the millions of consumers who purchase lighters with safety features. Safety features in lighters were required ‘after research showed children under the age of 5 playing with cigarette lighters had ignited an average of 5,900 residential fires resulting in 170 deaths and 1,150 injuries each year between 1986 and 1988’ according to Tampa Bay Online reporter Silvestrini in her 2010 article. Considering the need for safety features that are reliable in lighters, altering reports to skew the results of safety tests could have put many people and households in danger.
Pressure ulcer or bedsores as it is called is commonly referred to as very prevalent among high-risk patients, especially those confirm to hospital or long-term care setting. These individuals may be adults, elderly, frail, poorly nourished, and with comorbid illness. The objective of this assignment Is to Provide Awareness to my PICOT question which will be a quantitative research and will be supported by evidence-based research and obtained by systematic review from many database searches.
Jaul, E. (2010). Assessment and management of pressure ulcers in the elderly: current strategies. Drugs & Aging, (4), 311.
This qualitative study by Gorecki, Nixon, Madill, Firth, and Brown (2012) was conducted to ascertain the health-related quality of life (HRQL) as an important and relevant outcome in patients suffering pressure ulceration and the various factors that affect it. Pressure ulcers (PUs) are areas of necrosis and ulceration where tissues are compressed between bony prominences and hard surfaces.
The specific groups I will be comparing will be patients over the age of 18 during their hospital stay. I will be looking at how the use frequent turning my help prevent pressure ulcers compared to not receiving the frequent turning. After the pressure ulcer is developed I will examine the different treatments available for healing. I am interested in the specific outcome of having no significant pressure ulcers on any patient. This is to ensure patient safety and their well-being. As stated before pressure ulcers can cause big problems including death. If a pressure ulcer has developed some outcomes for that would be wound size reduction, loss of pain and sensitivity to that area, preventing sepsis, and eventual
The surveys were conducted between 1989 and 2005 predominantly in the US and showed an increase of 4.4% in number of nosocomial pressure ulcer prevalence rated with increase 6.3% in overall pressure ulcer prevalence rates. Nosocomial pressure ulcer prevalence rates were highest in long-term acute care facilities with anatomical location of greatest number of pressure ulcers being sacrum, hells and buttocks. The surveys also revealed that majority of Stage IV pressure ulcers were related to patients with dark skin: N=447,930 (total number of patients in survey), n1=1024 (dark skinned patients), n2 = 164 (dark skinned patients with Stage IV pressure ulcers). The incidence rates of pressure ulcers averaged at 5.4% which correlated with contributing factors of Braden Scores less than 18, serum albumin levels less than 3, fecal/urine incontinence, fragile skin and
The conclusion is that due to the amount of time the “e-cig” or the vape pens have been on the market more research is required to look at its short and long-term safety effects on a smoker's health. The use of second generation vaporizers considerably reduce cigarette consumption without causing significant side
With many decades worth of health data now available, it has never been clearer that smoking is one of the most dangerous habits a person can engage in. It is no wonder, then, that so many smokers are committed to quitting and improving their health.
The INTACT trial showed a significant reduction in pressure ulcers (PU) incidence in the intervention group at the hospital (cluster) level, but this difference was not significant at the
Vanderwee et al. (2007) aimed to overcome this by undertaking a snapshot study measuring the prevalence of pressure ulcers across Europe. Using the same methodology for all centres and including the details of 5947 patients, the study found 18.1% of patients had a grade 1-4 pressure ulcer, and only 9.7% received adequate preventative care. Although promising, this study is not without limitations. The voluntary nature of the study could lead to participant bias towards practice areas with more favourable pressure ulcer outcomes, ultimately leading to non-representative results. Additionally, a key limitation of snapshot studies is that the results are only applicable to that specific moment in time, bringing into question the generalisability of the findings to current
Usable lifetime consumption data were available for 118 of the 153 WP-only smokers, and 91 of the 103 cigarette-only smokers. Total hours of lifetime consumption was dichotomized at meaningful cut points for the dose response analysis as follows: WP hours were dichotomized into 78 hours and less versus greater than 78 hours. Seventy-eight hours corresponded to approximately two (2) WPs per week for one year. Lifetime cigarette hours were dichotomized at 730 hours or less versus greater than 730 hours. This cut point corresponded to approximately two (2) packs of cigarettes per week for one year. These cut points divided the cases into approximately even group sizes. The numbers of WP-only smokers were 58 and 60 for low and high doses, respectively.
A weakness within the study was the authors inability to use 40.8% of hospital patients participation in the pain prevalence study, this was due to illness, difficulty of assessment or patients were unavailable either off the floor 24%, or in isolation (Briggs, et al., 2013). Another strength within the study was the authors decision to use the 1998 European Pressure Ulcer Advisory Panel classification (EPUAP), the reason for this was that the updated version for 2009 was not being used at the participating hospitals, and this classification was familiar with the staff doing the skin assessments, allowing for all participating hospitals to have the same standards of skin classification in place (Briggs, et al.,
The title of the research paper is short and uncomplicated as not to mislead readers (Parahoo, 2014). It clearly and accurately states the intention and purpose of the research in a brief sentence that is easy to understand (Taylor, 2015). The title conveys key information including the population (participants with pressure ulcers) (PU), the intervention to be used (oral nutritional supplement) (ONS) and the desired outcome (healing) (Polit and Beck, 2014) to aid the readers understanding. The title also highlights that a randomised control study method was used, this aspect of a title is regarded as helpful to the reader as it conveys the approach used by the researchers (Taylor, 2015).
Throughout the study, fifty two patients were enrolled as participants. All participants were women that ranged in age from 32-74. In addition, of all fifty two participants twenty-four patients never smoked, twenty-four patients were prior smokers, and four patients never smoked (Boltong et al., 2014). According to Polit and Beck, the greater the sample size; the better the representation of the sample it will be (2017). Therefore, the greater the sample size, the most factual and accurate the research study will be considered (Polit & Beck, 2017). Within the selected study, even though the sample size is not ideal, the sample is still appropriate for a cohort study and is representative enough to conclude