OPTIMIZING AND VALIDATING THE HYPOTHALAMIC HUNGER REGULATION MATHEMATICAL MODEL
Ms. Divya1, Dr. Saurabh Mukherjee2
1Research Scholar, 2Associate Professor, Department of Computer Science, AIM & ACT, Banasthali University, Banasthali-304022, email: jangid.divya@gmail.com
Hypothalamus has a significant effect on the physiological functions of human body like Hunger regulation, Energy balance etc. A mathematical model is being developed which mathematically explains the functionality of Hunger Regulation. Some hormones also acts effectively during this process plays as important role in this model. Hypothalamic Hunger RegulationMathematical Model (HhRM). We are using statistical optimization tools to optimize and validate this Model. The
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This Hunger Regulation process is simulated with the help of Hypothalamic Hunger Regulating Mathematical Model (HhRM)[2]. HhRM is a mathematical approach for this homeostatic function of human body.HhRM divided into five different steps. Each step represents the combination of mathematical functions and variables. A simple binary function G (h) shows that whether the hormones are secreted by internal organs or not. The hormonal signals explain by the random numbers.Daubechies Wavelet function interprets the movement of Hormonal signals through Vegal Nerve.The response to the Hormonal Signals is being generated by the hypothalamic receptors. For this the concept of signal generation is used with scaling function with Entropy. The receptors signals transferred to Central Nervous system.
The mathematical model HhRM is as follows: dH/dt = G^ ' (h)+f(h)D4^ ' (h)+ Em(s)Sc '(s)
WheredH/dtis the change in the processing of Hypothalamus, H with respect to Time t, G(h) is the binary function f(h) is fractal function, D4’(h) is the Daubechies function, Em(s) is entropy measure and Sc’(s) scaling function.
2. Objective
The objective of our study is to optimize the mathematical model HhRM. In previous version of HhRM the simple scaling function was being used. Here our objective is to study
Scientifically, it has been proven that one should not make long-term decisions while hungry. Students at the University of Gothenburg in Sweden studied whether or not it is smart to make a decision when you are ravenous. A hormone that is made in the gastrointestinal tract, called ghrelin enhanced this study. Ghrelin is released when your body is searching for food as energy. When you are no longer hungry, the manufacturing of ghrelin halts. Ghrelin is also associated with drug and alcohol intake. Tests were developed to demonstrate how this happens through living organisms, the researchers at the University of Gothenburg examined rats. Although rats are not humans, they can display human-like behaviors. When an extra amount of ghrelin was inserted into the rat, they went against their regular impulses. They would gain a
In the scientific method lab, I explored the different food options for mice in order to find the best one that will help them gain weight. To succeed in this lab, I needed to examine several types of foods including fruits, raw meat, cooked and uncooked foods. In this experiment I used cooked macaroni as a positive control and for the negative control I didn’t feed the mice any food, only water. The main objective of this study was to determine the best solution that will help me understand the metabolism of mice. All mice used in this study were given the same resources, but the only difference was the different types of foods fed to the mice to understand the changes of weight gain or loss between the mice.
Scientifically, you should not make long-term decisions while hungry. Students at the University of Gothenburg in Sweden studied if it is smart to make a decision when you are ravenous. A hormone that is made in the gastrointestinal tract, called ghrelin enhanced their study. Ghrelin is released when your body is searching for food as energy. When you are no longer hungry, the manufacturing of ghrelin halts. Ghrelin is also associated with drug and alcohol intake. The researchers at the University of Gothenburg examined rats. Yes, rats are not humans, but they can display human-like behaviors. When an extra amount of ghrelin was inserted into the rat, they would go against their regular impulses to gain a quick amount of sugar instead of waiting a little bit longer for a larger, more substantial prize. A very much known phrase is you should never go food shopping while you are hungry. We all have
c) What other hormones could affect Mitchell’s appetite? Where do these hormones originate, and what are their effects? Use the textbook and the resources from the resource
<! DOCTYPE html> Practice Lab Assignment Lab Assignments Assignment 1 Assignment 2 Assignment 3 Assignment 4 Lab Practica Practicum 1 Practicum 2 Course Title: IT 207, Section: 002, Semester Fall 2015 Instructor: Omar Nachawati University: GMU
Norton (Ed.). (2006). Computing Fundamentals. [University of Phoenix Custom Edition e-Text]. New York, New York: McGraw-Hill. Retrieved January 21, 2011, from CIS105 - Computers-Inside and Out.
There are two theories on why we get hungry; these theories are called the Set or Settling Point theory, and the other is the Positive – Incentive theory. The Set or Settling theory differs a bit in the point of optimal weight (or fat/energy level) however the basic idea is the same. In this theory everyone has a set point (or an equilibrium) where the body is using the stored energy, and if the body is above this point then it does not become hungry if it is below the set point the body is lacking
Maria Konnikova in her essay “Why Do We Eat, and Why Do We Gain Weight?” talking about how our bodies deal with hunger. Why do eat more than we actually need? Obesity is a big problem nowadays and we don’t really know how to deal with it. A lot of times we call oversized people lazy and say that they can’t control what they eat. But how many times we caught ourselves of not being able to stop eating even though we were already full? How does it work that we can’t resist food? It’s because we’re unaware of what’s going on in our bodies. All the chemical reaction and tricks that our body can serve us leads to false hunger that we feel. We have to learn to read the signals that our body is sending us, to stay healthy. There’s a lot of research that explains how our body deals with hunger.
The hypothalamus dysfunction theory would suggest that animals have a “set weight” which is correct for their body, if this weight should increase or decrease then the body should make adjustments to regulate food intake to their “set weight”.
Hypothalamus is involved with emotions, thirst, hunger and is in charge of the nervous system. Hypothalamus adjusted temperatures in your body and tells the driver if they are hungry or thirsty.
he simulations presented exemplify how the simulation models can be used by the nutritionist to make decisions for precision nutrition.
acute effects of leptin on synaptic plasticity in the arcuate nucleus of the hypothalamus. The arcuate nucleus is one of the key targets of circulating hormones such as leptin. At least two distinct populations of neurons with opposing actions on food intake residein the arcuate nucleus, " (p.63). Pinto's data is ultimately described as helpful but also created many more questions, probably more than it answered.
Internally, the hunger we feel is conceived from the brain. It has once occurred to me that I did not realize lunch time passing because I was too busy working. This is clear proof that internal influence of hunger is by the brain and not the stomach (Hockenbury and Sandra 63). The brain part that regulates the hunger feeling is called hypothalamus. This segment of the brain is separated into the lateral and
The food that we consume is well assimilated in our body and is used for the growth and maintenance of body tissues. Life cannot exist without food, and it is for this reason that every living organism strives to obtain its food requirements. It has been seen that the satisfaction of hunger is usually the main factor for a satisfactory food intake. It is very important that for sustaining a healthy and normal life, diets should be planned with the scientific knowledge of nutrition. It is very essential to learn the general principles and considerations that govern the planning of balanced diets.
Submitted in partial fulfillment of the requirements for the degree of Bachelor of Engineering in Computer Engineering