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Respiratory Papillomatosis In Children Summary

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The article I chose “The Ethics of Managing Recurrent Respiratory Papillomatosis in Children: A Case
Study.” Discusses the use of off label medications to treat children with rare recurring medical
Illnesses and the ethical decisions that healthcare providers face in using them. Off label medications are those described as being used in a manner which is either not specified in the medication insert or is not an accepted standard treatment. Within this case study there are three off label medications used, they are Gardasil, the quadrivalent HPV vaccine for HPV stereotypes 6,11,16,18 and
Propranolol a beta blocker. The case study presents a three year old Malay boy who presented with stridor and hoarseness lasting approximately a week. …show more content…

It was during this procedure that multiple papillomatosis warts were seen on the vocal cords and in the Surrounding tissues. Further examinations confirmed the diagnosis of laryngeal papillomatosis. This rare disease is caused by the human papillomavirus, or (HPV) infection in the throat. It causes tumors to develop over a period of time in the throat and has the potential to be fatal as the growths can obstruct the airway. Surgical micro-debridement was done for the patient and resulted in favorable results of the stridor during post op. The patient experienced several recurrences and required that the patient undergo several surgical procedures. Eventually the patient was referred to a Pediatric team to possibly undergo therapy using an off label medication. In this case, Gardasil being one of them and the other being propranolol. Both which had trialed very poorly in clinical trials. The article discusses the ethics behind rather or not the patient should have been given to this young Patient when the in trials these medications didn’t perform very well. As well as the criteria, individual and ethical decisions that have to be made on a case by case basis amongst a team of medical providers. Prior

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