(1) Which statement about glycolysis is FALSE?
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- (a) Starting with one molecule of glucose, how many ATPs are produced during (I) aerobic and (II) anaerobic respiration? (b) In chemiosmotic (oxidative) phosphorylation, what is the most direct source of energy that is used to convert ADP + Pi to ATP and what the driving force for the ATP formation through ATP synthase?Consider the energy budget of glycolysis as a whole a) How many ATP's are made total? b) How many ATP's are invested (ATP --> ADP + Phosphate) c) How many ATP's does glycolysis of one glucose molecule net for the cell?(i) Briefly explain the glycerol phosphate shuttle, a pathway by which a reduced coenzyme in the cytosol passes its reducing power to a mitochondrial molecule. (ii) Compare the ATP yield of two molecules of glycerol which enter glycolysis versus one molecule of glucose in glycolysis.
- State whether each statement is true or false. If the statement is false, correct it so it can be true. (a) Oxidative phosphorylation generates heat by converting ADP to ATP. (b) The effects of a poison on actively respiring mitochondria are being studied to determine its mode of action. When the poison is added, all proteins and Q in the electron transport chain are in the reduced form, and ATP production stops. (Assume electron transport is continuously occurring.) This means that the poison could be inhibiting complex I.Write a one-sentence explanation for each of the following statements. (a) When the charge index is 1, the cell will not proceed for glycolysis. (b) Glycolysis evolved earlier than photosynthetic organisms. (c) Gluconcogenesis is not a reversal of glycolysis.In the Cori cycle, the lactate product of glycolysis in muscle is transformedback into glucose by the liver. (a) List the enzymes involved in the lactate → glucose pathway. (b) What is the net gain/loss of ATP for one round of the Cori cycle (glucose → lactate → glucose)?
- The pathway that converts glucose to acetyl-CoA is often referred to as an “aerobic oxidation pathway.” (a) Is molecular boxygen involved in any of the steps of glycolysis? (b) Thinking back to Chapter 20, where does molecular oxygen enter the picture?Glycolysis yields an immediate net gain of _______molecules for the cell. (a) 1 ATP (b) 2 ATP (c) 4 ATP (d) 32 ATP.a) How many moles of ATP can be gained from the catabolism of the following substrates to pyruvate? 2 Mole mannose 2 Mole lactose mole glycerol. b) Name three metabolic processes in the cell that are enhanced and two that are inhibited in response to the hormone insulin
- .Which of the following statements about glycolysis is correct? a) Glycolysis is an aerobic process (aerobic) b) Glycolysis takes place in the mitosol c) Glycolysis gives 2 moles of ATP compared to 1 mole of glucose d) Glycolysis cannot be reversed11) To which molecule is Glucose broken down in the process of glycolysis? What happens with pyruvate in the presence of oxygen (hint: it will enter a cell organelle to feed into chemical reactions called....) 12) Which molecule carries energy rich electrons from the intermediates of the citric acid cycle to the electron transport chain. NADH 13) Which of the following states (of this electron carrier) carries energy rich electrons: 1) NAD+ 2) NADH? 14) Is oxygen required for aerobic respiration to take place? In which step of aerobic respiration is oxygen required? 15) Define fermentation? 16) Which of the three steps of aerobic respiration can take place in absence of oxygen? 17) What is the fate of pyruvate in absence of oxygen (e.g., when oxygen consumption exceeds oxygen intake during intense exercise)?Which of the following enzymes CANNOT be found in the skeletal muscle? Glucose-6-phosphatase Glycogen synthase Glycogen phosphorylase Adenylyl cyclase Hexokinase Which of the following processes do NOT produce CO2? (1) Fatty acid synthesis (2) Oxidative deamination(3) Preparatory phase of glycolysis (4) Pentose phosphate pathway (1) and (2) only (2) and (3) only (2) and (4) only (1), (3) and (4) only (1), (2), (3) and (4) _______________ is an intermediate metabolite linkage between carbohydrate and fat metabolism. A. MalateB. CitrateC. Acetyl-CoA D. AspartateE. α-ketoglutarate ______________ transfers carnitine from mitochondrial matrix to cytoplasm during the transport of fatty acid to mitochondria. Carnitine acyltransferase I CarnitineacyltransferaseII Transaminase Translocase Citric acid shuttle