1. Propose a detailed stepwise mechanism, using curved arrow notation, for the following.H+Ha.b.H₂O, heat1. LiAlH4 (xs)2. H₂OOHH-NH2. In the synthesis of peptides, carboxylic acids are condensed with amines in the present of a reagentsuch as dicyclohexylcarbodiimide (DCC) [Section 25.6].a. Propose a mechanism for the following, using curved arrow notation.°DCCH₂NH₂NOHOHH₂NglycineglycineOHЯнзонgly-gly

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Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter4: Acids And Bases

Section: Chapter Questions

Problem 4.52AP

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tert-Butoxycarbonyl azide was developed as a reagent for peptide synthesis at OWL's home institution, the University of Massachusetts, by Prof. L.A. Carpino. It is prepared by treating tert-butoxycarbonyl chloride with sodium azide. Propose a structure for the initially-formed intermediate in this reaction.
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GRYH3CIVMw5TIcrq7vnq/w/wiewform?edit_requested3true#settings can be obtained by using 17. The preparation of Benzenesulphonic from benzene by reacting it with oleum. phenols phenyl alanine Sulfobenzene 18. The reaction of the carboxylic acid with an alcohol and an acid catalyst leads to the formation of ester (along with water), is called O Halogenation Haloform reaction Fischer esterification. 19 are highly inflammable and they form extremely explosive mixtures with air giving CO2 and water. " Esters Ethers 47 Amides
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