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- 1. Lit :E 2. HCI Br2, H20 Isunepe enc toss1gwolol ert to rlose 107 (2nion S bonsdmun ed bluorde yisaeesen li ele bensdr CI 18 LICH3 HO 1emonsne+ CI H. (MCPBA) rt ol egete bns ainepssonitail elesrinye biewiols s2ogon9 (niog E E eluoslom e pelom CH3OH catalytic H2SO4HO HO. OH base CI EIO- C-OEt epichlorohydrin OH NaOEt 2,6-dihydroxy- acetophenone *Na O2C. .CO2 Na* NaOH, H2O II OH Cromolyn sodium Cromolyn sodium, developed during the 1960s, has been used to prevent allergic reactions primarily affecting the lungs, as, for example, exercised- induced emphysema. It is thought to block the release of histamine, which prevents the sequence of events leading to swelling, itching, and constriction of bronchial tubes. v Cromolyn sodium is synthesized in the above series of steps. rch 31% 11:24 P 4/20/20-Which one is the electrophilic site? d CH3 H H3C-C-C-ÖH H H H: O a. b O b. d О с. a O d. c
- التاريخ تليله : Egbgbl You need to prefare l:5Lof 25 Wy Solutionof adurg, how much activeingredient is cequired?Scheme 4. Burdick et al. Preparation of CBD ONa EtO₂C CO₂Et da C5H11 NaOEt/EtOH 99% 8 OH Br. CO₂Et H₂/Pd-C EtOH C5H11 72% HO HO inw Br 10 HO OH 12 CO₂Et NETARIO C5H11 gra NaOH MeOH A 44% HO OH 11 9 CO₂Et C5H11 CBD CO₂Et Br₂ Асон C5H11 86% 4 10% Sc(OTf)3 MgSO4 CH₂Cl₂/3 h 87%Identify the electrophilic site in each of the molecules shown. а Br O d Compound A Compound B H3C CH3 a C d. e Identify the electrophilic site in compound A. Identify the electrophilic site in compound B. a a d.
- Modifica Vista Vai Strumenti Finestra Aiuto Sab 22 m D. Hydroxyacids.pdf Pagina 41 di 49 Q Cerca Aa v Task 9. Write the structural formulas of the following compounds: a) 3-oxobutanoic acid; c) 3,3-dimethyl-2-oxobutanoic acid; e) 2-methyl-4-oxopentanoic acid; g) glyoxylic acid ethyl ester. Task 10. Name the following compounds:Which statement is INCORRECT? Select one: O A. The presence of oxygen and nitrogen containing functional groups in a drug usually enhances the lipophilicity OB. O C. The metabolism of drugs can involve demethylation and glucuronidation COX-1 & COX-2 are classified as NSAIDs OD. COX-1 and COX-2 synthesise inflammatory prostaglandins Course Hero 4 JD Course Hero 2 EPY C Please rat Q+ Exam.pdf - Study more efficiently and get your q. по N earn unlocks. 88 21°C ^ @ @ ↳ # X HOJ > 오후 10= 2023-06-a) LDA b) CN Br DIBAL -OTHP THP MCPBA Hydrazine H₂N-NH2 KOH heat dil. HCIO4 -OH OH CN -OTHP