3. The following sequence comes from a synthesis of strychnine. Fill in the reagents to complete the synthesis fragment shown. TBSO OTBS MEOCH,CI, IPr;NE! 1. Lil, DMSO 2. Boc,0. DMAP Meo,c co,Me TBAF DEAD, PPh. NSNH,

3. The following sequence comes from a synthesis of strychnine. Fill in the reagents to complete the synthesis fragment shown. TBSO OTBS MEOCH,CI, IPr;NE! 1. Lil, DMSO 2. Boc,0. DMAP Meo,c co,Me TBAF DEAD, PPh. NSNH,

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter23: Enzymes

Section: Chapter Questions

Problem 23.91P

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Question

3. The following sequence comes from a synthesis of strychnine. Fill in the
reagents to complete the synthesis fragment shown.
TBSO-
OTBS
MEOCH;CI, iPr,NEt
1. Lil, DMSO
*"OH
2. Boc,0, DMAP
Meo,c co,Me
TBAF
DEAD, PPh
NSNH,

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