A peptide with the sequence isoleucine1-aspartate2-valine3-lysine4-proline5-glutamate6 is located at the surface of a protein. Which residues are likely oriented toward the interior of the protein and what is the most likely secondary structure that this peptide is in? a.) Residue numbers 2, 4, 6; alpha helix b.) Residue numbers 1, 3, 5; alpha helix c.) Residue numbers 1, 3, 5; beta sheet d.) Residue numbers 2, 4, 6; beta sheet
A peptide with the sequence isoleucine1-aspartate2-valine3-lysine4-proline5-glutamate6 is located at the surface of a protein. Which residues are likely oriented toward the interior of the protein and what is the most likely secondary structure that this peptide is in?
Amino acids combine to form proteins by the formation of peptide bond. Amino acids have a one amino group, one carboxyl group, one hydrogen and one R group or side chain. There are 20 amino acids and side chain will vary in all of them. Amino acids can be classified on the basis of side chain as
- Hydrophobic uncharged amino acid
- Polar uncharged amino acids
- Charged amino acids
Hydrophobic amino acids will have non-polar side chain. There are 9 amino acids that are hydrophobic in nature. Polar amino acids will have polar side chains that are not charged. Charged amino acids will either have positively or negatively charged side chain.
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