An 84 year old male patient has been given a loading dose of digoxin of 298 micrograms in divided doses by intravenous infusion. He has a creatinine clearance (Ccr) of 34 ml / min. What is the maintenance dose (in micrograms) that this patient should receive? Round your answer to the nearest whole number. Use the formula provided to calculate the maintenance dose. Maintenance Dose = Peak body stores x % daily loss 100 Where: Peak Body Stores = Loading Dose % Daily Loss = 14 + Creatinine clearance (Ccr) 5

An 84 year old male patient has been given a loading dose of digoxin of 298 micrograms in divided doses by intravenous infusion. He has a creatinine clearance (Ccr) of 34 ml / min. What is the maintenance dose (in micrograms) that this patient should receive? Round your answer to the nearest whole number. Use the formula provided to calculate the maintenance dose. Maintenance Dose = Peak body stores x % daily loss 100 Where: Peak Body Stores = Loading Dose % Daily Loss = 14 + Creatinine clearance (Ccr) 5

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter13: Dimensional Analysis/units Conversion

Section: Chapter Questions

Problem 1SST

See similar textbooks

Similar questions

Colin who is 78 years old has been admitted to a ward where you are working, with acute bacterial meningitis. The duty doctor wants to treat with meropenem and she would like to know what dose to treat with. In Colin’s notes you see that he has a history of kidney injury, you have his weight which is 49kg and his serum creatinine is 157micromol/L. What is Colin’s estimated creatinine clearance? X([140-age] × weight in kg)/(serum creatinine IN micromol/L Where X =1.04 for female and X= 1.23 for male 2. What is the maximum daily dose (in grams) of meropenem that Colin will receive?
Colin who is 78 years old has been admitted to a ward where you are working, with acute bacterial meningitis. The duty doctor wants to treat with meropenem and she would like to know what dose to treat with. In Colin’s notes you see that he has a history of kidney injury, you have his weight which is 49kg and his serum creatinine is 157micromol/L. What is Colin’s estimated creatinine clearance? 2. What is the maximum daily dose (in grams) of meropenem that Colin will receive?
A 72-year-old adult patient who weighs 78 kg is prescribed by the doctor “Potassium Chloride 40meq in 1L to run for 8 hours” via the peripheral line for a potassium level of 3.3 mEq/L that was drawn this morning. Note: 10 mEq of potassium chloride increases serum potassium levels by approximately 0.1 mEq/.L The concentration of potassium for intravenous administration via a peripheral line should not exceed 40mmol / 500 mL 10 mEq/hr maximum infusion rate; not to exceed 200 mEq dose/24hr Administration rates above 20mmol/hour require cardiac monitoring. How much will the order medication “Potassium Chloride 40meq in 1L to run for 8 hours” raise the patient's potassium level in a day? Is it still within the normal potassium serum levels, which is 3.5–5.0 mEq/L? Does the order comply with the maximum concentration of potassium to be administered peripherally? Does the order’s infusion rate do not exceed the standard maximum infusion rate? Does the order require cardiac monitoring?
Mrs B, aged 43 years, weight 56 kg, requires a loading dose of drug B. The target plasma concentration is 18.9 mg/ L, volume of distribution is 0.5 L/ kg, the salt factor is 0.9 and bioavailability fraction is 1. What is the intravenous loading dose (LD) of Drug B in milligrams (mg)? units - mg LD = Cp desired x Vd S x F Where Cp desired is the target plasma concentration; Vd is the volume of distribution; S is the salt factor and F is the bioavailability fraction
Determine the maintenance dose (in mg) of tobramycin for a 65 year old male patient weighing 85 kg and measuring 5 ft 7, in. in height with a serum creatinine of 2.8 mg/dL. The loading dose desired is 1 mg/kg of ideal body weight and 1.8 mg/kg of ideal body weight for the maintenance dose. Report your answer as a whole number.
A 30-year-old female patient with uncontrolled hypertension is suspected by an investi- gating endocrinologist of having Conn's syndrome. Results of routine biochemistry were (reference ranges are given in brackets): Sodium Potassium Urea Creatinine Alkaline phosphatase Alanine aminotransferase Albumin Bilirubin Calcium 146 mmol/L 2.1 mmol/L 7.2 mmol/L 146 μmol/L 290 IU/L 20 IU/L 49 g/L 8 μmol/L 2.19 mmol/L (135-145) (3.5-5.0) (3.5-6.6) (70-150) (95-320) (5-42) (35-50) (<17) (2.12-2.62) (a) Are any of the electrolyte concentrations abnormal, and if so what condition is suggested? (b) What further biochemistry investigations would you undertake? Explain your reasoning.
Mrs B presents you with a prescription for warfarin tablets 1 mg. The directions are to take 6 mg at 6pm that evening, followed by alternating daily doses of 4 mg and then 3 mg (as long as her INR remains within the recommended range). What is the exact number of warfarin 1 mg tablets required for a 28 day supply assuming her INR remains in range?
In pediatric systolic or pulseless arrest, Epinephrine (1 mg/mL, 1mL amp) is dosed at 0.01mg/kg with a maximum single dose of 1mg every 3-5 minutes until with ROSC. Epinephrine is prepared by mixing 1mg of Epinephrine with 9mL of NSS, and this is the stock solution in which the doses to be administered are aspirated.Patient YH, weighing 26kg, was found unresponsive and pulseless. ACLS was started. What is the appropriate volume (in 2 decimal places) to be aspirated from the Epinephrine admixed solution per dose?
A 71-year-old man with enterococci infection is started treatment with 240 mg of intravenous gentamicin. It has a volume of distribution of 30 L, a half-life of 4 hours, and demonstrates first-order and one-compartment kinetics. Which of the following is the most likely serum drug concentration 8 hours later? 0.5 mg/L 1 mg/L 1.5 mg/L 2 mg/L 3 mg/L
Assume that Ali (same patient in question 1) was prescribed vancomycin 1000 mg every 36 hours. After few days, Steady-state vancomycin concentrations were obtained before and after the fourth dose, and the peak concentration (obtained ½ hour after a 1- hour infusion of vancomycin) was 34 µg/mL while the trough concentration (obtained immediately before dosage administration) was 2.5 pg/mL. Compute a revised vancomycin dose for this patient to provide a steady-state peak concentration of 48 ug/mL and a steady- state trough concentration of 17 pg/mL. a. Estimate new rate constant (Ke) and half-life (t1/2) b. Estimate volume of distribution (Vd) using this equation Cmaxss + Cminss C. Calculate the new dose interval d. Calculate the new dose
6) A male patient has been given a loading dose of digoxin of 1000 micrograms in divided doses by intravenous infusion. He has a creatinine clearance of 47ml/minWhat is the maintenance dose (in micrograms) that this patient should receive? Use the formula provided to calculate the maintenance dose. Maintenance Dose = Peak body stores x % daily loss100Where:Peak Body Stores = Loading Dose% Daily Loss = 14 + Creatinine clearance (Ccr)/5
The peak plasma concentration achieved after the first IV dose of drug X is 25 mg/L. The drug’s half-life is 3.5 hours, and it is administered every 12 hours. What will be the peak plasma concentration at steady state?