Based on the experimental results shown in the table, Identify whether the inhibitor acting on this enzyme is a competitive inhibitor or a non-competitive inhibitor, and Explain the reason logically.

Organic And Biological Chemistry
7th Edition
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:STOKER, H. Stephen (howard Stephen)
Chapter10: Enzymes And Vitamins
Section: Chapter Questions
Problem 10.48EP
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4-1
Based on the experimental results shown in the table, Identify whether the inhibitor acting on this enzyme is a
competitive inhibitor or a non-competitive inhibitor, and Explain the reason logically.

4-2
In 4-1, the concentration of the enzyme competition inhibitor was 1×10-3M. If 1 µmol of the inhibitor is present in
the 1 mL reaction mixture, Indicate how much the initial degree of hydrolysis decreases as a proportion(in the
presence of inhibitors/in the absence of inhibitors) with respect to the absence of inhibitors. 

4-1
Based on the experimental results shown in the table, Identify whether the inhibitor acting on this enzyme is a
competitive inhibitor or a non-competitive inhibitor, and Explain the reason logically.
Substrate concentration
(mol/L)
0.0001
0.00015
0.0002
0.0005
0.00075
Reaction rate (µmol/min)
Inhibitor (Absence)
28
36
43
65
74
Inhibitor(2.2 × 10-4 M)
17
23
29
50
61
Transcribed Image Text:4-1 Based on the experimental results shown in the table, Identify whether the inhibitor acting on this enzyme is a competitive inhibitor or a non-competitive inhibitor, and Explain the reason logically. Substrate concentration (mol/L) 0.0001 0.00015 0.0002 0.0005 0.00075 Reaction rate (µmol/min) Inhibitor (Absence) 28 36 43 65 74 Inhibitor(2.2 × 10-4 M) 17 23 29 50 61
4-2
In 4-1, the concentration of the enzyme competition inhibitor was 1×10-³M. If 1 µmol of the inhibitor is present in
the 1 mL reaction mixture, Indicate how much the initial degree of hydrolysis decreases as a proportion(in the
presence of inhibitors/in the absence of inhibitors) with respect to the absence of inhibitors.
Transcribed Image Text:4-2 In 4-1, the concentration of the enzyme competition inhibitor was 1×10-³M. If 1 µmol of the inhibitor is present in the 1 mL reaction mixture, Indicate how much the initial degree of hydrolysis decreases as a proportion(in the presence of inhibitors/in the absence of inhibitors) with respect to the absence of inhibitors.
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