Which of the following mechanisms of action could the drug from the above question potentially have to cause the described effects in male rats (so disruption of male sexual behavior when given prenatally but not when given in adulthood)? Group of answer choices Estrogen receptor antagonist or aromatase inhibitor Testosterone receptor antagonist Estrogen receptor antagonist Aromatase inhibitor
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Which of the following mechanisms of action could the drug from the above question potentially have to cause the described effects in male rats (so disruption of male sexual behavior when given prenatally but not when given in adulthood)?
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- "hich of the following statements is true of the differences between methohexital and midazolam? Multiple Choice Midazolam produces analgesia at small doses whereas methohexital produces amnesia at anesthetic doses. Midazolam induces anesthesia quickly, but methohexital does not. Methohexital has a specific receptor antagonist but midazolam does not. Midazolam is available for rectal administrątion, whereas methohexital is administered intravenously.Describe a mechanism by which a steroid hormone might act to increase intracellular levels of cyclic AMP. Match the words in the left column to the appropriate blanks in the sentences on the right. activate decrease inhibit repressed induced increase Reset Help Since steroid hormone-receptor complexes specific genes, a steroid hormone could in principle transcription of the gene for adenylate cyclase and, hence, steady-state level of this enzyme. Other possibilities could include synthesis of a phosphodiesterase inhibitor or synthesis of cAMP phosphodiesterase. the transcription of theIn a breast cancer patient whose tumor cells express large amounts of estrogen receptors and are therefore very sensitive to estradiol, which of these drugs will be very effective in reducing plasma levels of estradiol and consequently the breast tumor growth? Group of answer choices Letrozole Paclitaxel Methotrexate Megestrol
- Explain how mutations in the following proteins might result in either loss of responsiveness to a given hormone or production of a continuous signal even in the absence of the hormone: a mutation in the regulatory (R) subunit of cAMP-dependent protein kinase, making R incapable of binding to the catalytic (C) subunitwhat Protien ligand interacts the EPH RECEPTOR EPHB2 and what drug binds to the receptor. give example and Include details of bidning and signalling.Seasonal affective disorder (SAD) is a mood disordercharacterized by, among other symptoms, increasedappetite, sluggishness, and increased sleepiness. It occursmost commonly during the winter months, especially inregions with long winter nights. Propose a role formelatonin in SAD and a possible non-drug therapy.
- Discuss the effective biological difference between testosterone and dihydrotestosterone (DHT).Pls explain in detail how the drug affected brain cells at the cellular or molecular level (do not just copy and paste on internet) Please write the details of each one Meth Opiate Receptor GABA Receptors Dopamine ReceptorThe rate limiting enzymes for norepinephrine is respectively. Aromatic catecholaminase; serotonin methylase tyrosine carboxylase; tryptophan carboxylase amino acid decarboxylase; tyrosine decarboxylase tyrosine hydroxylase; tryptophan hydroxylase and for 5-HT is
- Estrogen receptor antagonists inhibit tumors by: 1) blocking estrogen binding to receptors 2) binding cell-surface receptors 3) stimulating intracellular receptors 4) binding HER2 receptors and keeping agonists from bindingA patient is prescribed drug for the treatment of his prostate cancer that blocks testosterone from binding to its intracellular receptor. Which of the following drugs has this mechanism of action? Flutamide Tamoxifen Leuprolide SunitinibDexamethasone 1 Dexamethasone is a glucocorticoid administered as an anti-inflammatory agent and immunosuppressant. It is structurally similar to cortisol produced naturally by your adrenal glands. It treats a number of conditions including inflammation, arthritis, autoimmune conditions, skin and eye conditions, asthma, multiple sclerosis, blood or bone marrow disorders, different types of cancer (e.g. leukemia and lymphoma), and severe allergies. This medication is also administered to patients with severe COVID-19 symptoms to decrease mortality rates*. Given that it is a steroid, which family of macromolecules does dexamethasone belong to? *research from the University of Oxford, "Randomised Evaluation of COVID-19 Therapy" trial, recovery.net 2 Given the structures of dexamethasone (left) and cortisol (right) below, and that they both bind to the same receptor, would you expect the binding of dexamethasone to be to the active or allosteric site of the receptor? 3 Based on the…