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Briefly explain the term ‘chemoselectivity’
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- On the following page are three compounds, 1, 2, and 3, that have been investigated as anti-malarial candidates. Compound 1 is the "parent" molecule, and 2 and 3 are derivatives. Shown next to each molecule is (i) the enthalpy change when it binds to its target, and (ii) the dissociation constant for the molecule/target complex. Consider the structures and answer the following: AH = - 1.2 kcal/mol; Kp = 16 nM OH 1 HO AH = - 6.0 kcal/mol; Kp = 76 nM OH AH = - 5.5 kcal/mol; Kp = 0.5 nM OH 3 (i) What is the difference among 1, 2, and 3?True or false and why is false 1 There are 2 major classes of keratins: alpha keratins (found in mammals) and beta keratins (found in feathers and scales of birds and reptiles) 2 One estimate of mobility within a crystal is the B-factor that reflects spreading or blurring of electron density 3 In NMR, the longitudinal relaxation time (T1) reflects the rate at which magnetization returns to the longitudinal axis after a pulseWhat is the answer key to this?
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- Please enumerate and explain 1. WHAT ARE THE GENERAL RULES IN GRAMS STAINING CLASSIFICATION OF BACTERIA?A 35 year old male was taken to the hospital with excruciating pain in the lower abdominal area. It was discovered that this patient drank no more than half a glass of water each day over the past week, while drinking at least three cups of black tea on the same days. Additionally, the patient regularly eats very large quantities of spinach. Upon further analysis, it was determined that the presence of Calcium Iodideand Sodium Oxalate may have led to the pain that the patient was experiencing. Determine whether or not kidney stones could be the probable cause of the lower abdominal pain for this patient by answering the following questions (Be sure to show your work for all parts): Assume that Calcium Iodideand Sodium Oxalate are the starting substances (reactants) in the reaction: a. Write a balanced chemical equation describing the formation of kidney stones, using the information in the case study. b. State the names of the products that are produced from this reaction. c.…please explain the answer in detail
- A 35 year old male was taken to the hospital with excruciating pain in the lower abdominal area. It was discovered that this patient drank no more than half a glass of water each day over the past week, while drinking at least three cups of black tea on the same days. Additionally, the patient regularly eats very large quantities of spinach. Upon further analysis, it was determined that the presence of Calcium Iodideand Sodium Oxalate may have led to the pain that the patient was experiencing. Determine whether or not kidney stones could be the probable cause of the lower abdominal pain for this patient by answering the following questions (Be sure to show your work for all parts): Assume that Calcium Iodideand Sodium Oxalate are the starting substances (reactants) in the reaction: a. Write a balanced chemical equation describing the formation of kidney stones, using the information in the case study. b. State the names of the products that are produced from this reaction. c.…A 35 year old male was taken to the hospital with excruciating pain in the lower abdominal area. It was discovered that this patient drank no more than half a glass of water each day over the past week, while drinking at least three cups of black tea on the same days. Additionally, the patient regularly eats very large quantities of spinach. Upon further analysis, it was determined that the presence of Calcium Iodideand Sodium Oxalate may have led to the pain that the patient was experiencing. Determine whether or not kidney stones could be the probable cause of the lower abdominal pain for this patient by answering the following questions (Be sure to show your work for all parts): Assume that Calcium Iodideand Sodium Oxalate are the starting substances (reactants) in the reaction: a. Write a balanced chemical equation describing the formation of kidney stones, using the information in the case study. b. State the names of the products that are produced from this reaction. c.…Why should we develop different methods for the separation of chiral compounds in pharmaceutical analysis?