Calculate the degree of ionization of morphine, pKa 8.0, in a solution with a pH of 2.2. Predict how the degree of ionization could affect the ease of absorption of morphine in (a) the stomach and (b) the intestine when the pH of the stomach fluid is 2.0 and the pH of the intestinal fluid is 6.

Chemistry: Principles and Practice
3rd Edition
ISBN:9780534420123
Author:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Publisher:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Chapter16: Reactions Between Acids And Bases
Section: Chapter Questions
Problem 16.81QE: Write the chemical equation and the expression for the equilibrium constant, and calculate Kb for...
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Calculate the degree of ionization of morphine, pKa 8.0, in a solution with a pH of 2.2.
Predict how the degree of ionization could affect the ease of absorption of morphine in
(a) the stomach and (b) the intestine when the pH of the stomach fluid is 2.0 and the pH
of the intestinal fluid is 6.
Transcribed Image Text:Calculate the degree of ionization of morphine, pKa 8.0, in a solution with a pH of 2.2. Predict how the degree of ionization could affect the ease of absorption of morphine in (a) the stomach and (b) the intestine when the pH of the stomach fluid is 2.0 and the pH of the intestinal fluid is 6.
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