Cell A is a glutamatergic neuron with a single synapse onto Cell B. Which of the following events would NOT result in an increased postsynaptic response in Cell B caused by an action potential in Cell A? a. Increase in the amount of glutamate released from Cell A b. Increase in the number of AMPA receptors on the surface of Cell B c. Increase in the number of GABA receptors on the surface of Cell B d. Addition of more synapses between Cell A and Cell B e. These would all increase the postsynaptic response

Cell A is a glutamatergic neuron with a single synapse onto Cell B. Which of the following events would NOT result in an increased postsynaptic response in Cell B caused by an action potential in Cell A? a. Increase in the amount of glutamate released from Cell A b. Increase in the number of AMPA receptors on the surface of Cell B c. Increase in the number of GABA receptors on the surface of Cell B d. Addition of more synapses between Cell A and Cell B e. These would all increase the postsynaptic response

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 4TAHL: Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and...

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Which of the following does not contribute to propagation of action potentials? a. As the area outside the membrane becomes negative, itattracts ions from adjacent regions; as the inside of the membrane becomes positive, it attracts negative ions from nearby in the cytoplasm. These events depolarize nearby regions of the axon membrane. b. The refractory period allows the impulse to travel in only one direction. c. Each segment of the axon prevents the adjacent segments from firing. d. The magnitude of the action potential stays the same as it travels down the axon. e. Up to a limit, increasing the intensity of the stimulus increases the number of action potentials.
An example of a synapse could be the site where: a. neurotransmitters released by an axon travel across a gap and are picked up by receptors on a muscle cell. b. an electrical impulse arrives at the end of a dendrite causingions to flow onto axons of presynaptic neurons. c. postsynaptic neurons transmit a signal across a cleft to apresynaptic neuron. d. oligodendrocytes contact the dendrites of an afferent neurondirectly. e. an onoff switch stimulates an electrical impulse in apresynaptic cell to stimulate other presynaptic cells.
Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and presynaptic excitatory neuron B terminates on the same postsynaptic cell on a dendrite located on the side of the cell body opposite the axon hillock. Explain why rapid firing of presynaptic neuron A could bring the postsynaptic neuron to threshold through temporal summation, thus initiating an action potential, whereas firing of presynaptic neuron B at the same frequency and the same magnitude of EPSPs may not bring the postsynaptic neuron to threshold.
In the hippocampus, when glutatmate is released into the synaptic cleft, but the postsynaptic cell is NOT depolarized, there is only a small postsynaptic response. Why is this the case? A. Ca++ ions block the NMDA ion channel B. Mg++ ions block the NMDA ion channel C. Glutamate is an inhibitory amino acid neurotransmitter D. There are no NMDA receptors on the postsynaptic cell
Which of the following neuronal changes is associated with short term synaptic strength? O a. Changes in the size of neural spines o b. Changes in the shape of neural spines с. Increased production of neurotransmitter vesicles in the presynaptic cell o d. Increased buildup of Ca²+ in the terminal knob of the presynaptic axon О е. Increased expression of postsynaptic neurotransmitter receptors
Glutamate's effect when it binds with protein receptors on the post synaptic membrane is to: a. Initiate movement of potassium ions out of the membrane b. Initiate movement of sodium ions into the membrane c. Initiate movement of sodium ions out of the membrane d. Initiate movement of potassium ions into the membrane GABA is an example of an inhibitory neurotransmitter. Drugs that increase the level of GABA are used to treat diseases such as epilepsy where the signal transmission needs to be impaired. The effect of the inhibitory neurotransmitter on the postsynaptic membrane is to: a. hyperpolarize the postsynaptic membrane b. decrease the threshold level c. depolarize the postsynaptic membrane d. maintain the resting potential Calcium is vital for bone growth, but it's also an important part of neural transmission. Calcium is required for the axon terminal to: a. Reuptake the neurotransmitter via exocytosis b. The neurotransmitter to be released by endocytosis c. The neurotransmitter…
6. Identify the following structures on an image of a synapse: Postsynaptic neuron Presynaptic neuron Neurotransmitter Synaptic cleft Synaptic vesicles Receptor for neurotransmitter Cell adhesion molecules Axon terminal 7. hore CAFE Describe the actions of sodium and potassium during action potential generation as it relates to depolarization, repolarization, and hyperpolarization. State the directional flow of each ion and the state of the gated channels for each stage. See figure 12.15 in the textbook.
At a chemical synapse, an action potential triggers an influx of Ca²+ which .. Select one: O A. triggers the exocytosis of neurotransmitters. O B. interfere directly with IPSPS in the postsynaptic cell. O C. depolarize the synaptic terminal of the presynaptic neuron, causing an excitatory postsynaptic potential (EPSP) in it. D. bind to neurotransmitter receptors on the postsynaptic cell, causing an inhibitory postsynaptic potential (IPSP). O E. cause the fusion of synaptic vesicles with the postsynaptic membrane, releasing neurotransmitters into the synaptic terminals.
Fill out the following table (the 2 columns on the left) LTP LTD Is the following directly associated with the induction of LTP, LTD, both or neither (check both if both apply, and leave blank if neither apply)? a. Increased activity of phosphatase I b. Increased levels of presynaptic Ca²+ c. Postsynaptic hyperpolarization d. Removal of AMPA receptors from the postsynaptic membrane e. Postsynaptic depolarization f. Increased levels of postsynaptic Ca²+ g. Insertion of AMPA receptors into the postsynaptic membrane h. Presynaptic hyperpolarization
GABA is an example of an inhibitory neurotransmitter. Drugs that increase the level of GABA are used to treat diseases such as epilepsy where the signal transmission needs to be impaired. The effect of the inhibitory neurotransmitter on the postsynaptic membrane is to: Select one: a. decrease the threshold level b. hyperpolarize the postsynaptic membrane c. depolarize the postsynaptic membrane d. maintain the resting potential
Local anesthetics "block" the action potential and therefore do not allow "pain" information to proceed to the brain and spinal cord. In the presence of these molecules (local anesthetics) 'threshold' is essentially "ignored". The molecules most logically work by: 23. a. Decreasing the intracellular [potassium] b. Blocking the opening of the voltage-gated potassium channels c. Decreasing the extracellular [sodium] d. Blocking the opening of the voltage-gated sodium channels
Organophosphate pesticides inhibit the action of acetylcholinesterase. What effect does this have in the cell? Select one: a. It prevents synthesis of ACh in the presynaptic terminal causing less neurotransmitter release b. It prevents breakdown of ACh in the synapse causing increased activity at the postsynaptic cell c. It prevents reuptake of ACh into the presynaptic terminal causing increased activity at the postsynaptic cell d. It prevents binding of ACh on the postsynaptic cell causing less activity e. It prevents reuptake of ACh into the presynaptic terminal causing less neurotransmitter synthesis.