CHM3413-Neutral vs lonized consider the table of drugs shown below and their respective pka value(s). Complete the table by drawing the relevant portion of the drug molecule in its IONIZED form. Indicate whether the ion is the conjugate acid or conjugate base of the neutral drug, if two pka values are listed, then two ionized structures must be drawn. Drug Name Neutral Form (Neutral) pka from table Baclofen Captopril Ampicillin НА ВН+ 5.4 9.5 3.7 9.8 2.5 7.2 Doxycycline 3.4 95 2. 7.7 H H₂C HS yo NH₂ O OH OH NH S CH₂ fot OH ON lonized Form(s) Is/are the ION(s) a conj. acid or conj, base? CA or CB? % ionized at physiological pH?
CHM3413-Neutral vs lonized consider the table of drugs shown below and their respective pka value(s). Complete the table by drawing the relevant portion of the drug molecule in its IONIZED form. Indicate whether the ion is the conjugate acid or conjugate base of the neutral drug, if two pka values are listed, then two ionized structures must be drawn. Drug Name Neutral Form (Neutral) pka from table Baclofen Captopril Ampicillin НА ВН+ 5.4 9.5 3.7 9.8 2.5 7.2 Doxycycline 3.4 95 2. 7.7 H H₂C HS yo NH₂ O OH OH NH S CH₂ fot OH ON lonized Form(s) Is/are the ION(s) a conj. acid or conj, base? CA or CB? % ionized at physiological pH?
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 7.8P
Related questions
Question
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 4 steps with 3 images
Recommended textbooks for you
Essentials of Pharmacology for Health Professions
Nursing
ISBN:
9781305441620
Author:
WOODROW
Publisher:
Cengage
Essentials of Pharmacology for Health Professions
Nursing
ISBN:
9781305441620
Author:
WOODROW
Publisher:
Cengage