Corona-virus disease 2019 (COVID-19) is a new disease, caused by a novel (or new) corona-virus that has not previously been seen in humans. This virus can be a product of dark biotechnology? Explain why?
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Corona-virus disease 2019 (COVID-19) is a new disease, caused by a novel (or new) corona-virus that has not previously been seen in humans. This virus can be a product of dark
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- Corona-virus disease 2019 (COVID-19) is a new disease, caused by a novel (or new) corona-virus that has not previously been seen in humans. From the point of your opinion, this virus can be a product of dark biotechnology?Corona-virus disease 2019 (COVID-19) is a new disease, caused by a novel (or new) corona-virus that has not previously been seen in humans. This virus can be a product of dark biotechnology?The complete coronavirus genome sequence from the first known patient infected with SARS-CoV-2 was published on January 10th 2020, just a short time after the patient had been hospitalized in China with respiratory symptoms. They did this so quickly using nanopore sequencing. Scientists compared the genome sequence from the new coronavirus (SARS-CoV-2) with the genome sequences from several other coronaviruses and they did identify a sequence unique to the SARS-CoV-2 strain. This unique sequence was in the N gene of the viral genome. What protein is made from the N gene of the virus?
- Coronaviridae is a virus “family.” There are actually many different coronaviruses within this group, including less pathogenic virus strains that cause the common cold. Many people in this course have likely been infected with one of these other coronaviruses. A common feature of coronaviruses and other RNA viruses (think influenza virus, HIV, etc.) is that they mutate frequently. This is because the viral enzymes that copy the genome during replication can’t fix mistakes. Given this information, how might we be able to distinguish the SARS-CoV-2 strain from some of the other, less concerning, coronavirus strains?Some retroviruses that have a wide host range have been developed for use in treatment of diseases or syndromes. These viruses do not result in a productive infection because they lack critical genes for viral replication, but they do carry DNA sequences that allow them to be packaged into infectious particles. Once in the host cell the viral DNA is released and integrates into the cell's genome. The advantage to this strategy is that the delivery of the DNA is very efficient. What is one possible problem of using a virus that can integrate into the human nuclear genome? Multiple Choice The virus carries genes that will interfere with host cell activities. The viral DNA sequences could still cause a disease. Since the viral DNA sequences no longer contain essential genes for viral replication the host cell may not be able to replicate either. The integration could disrupt an essential gene or genes.Simian Virus 40 is carcinogenic in primates. 1). which molecule of the virus 2). what particular property of the molecule that enable the malignant transformation.
- When Wimmer and coworkers announced that they had synthesized the poliovirus, they created considerable controversy. Some people feared that deadly and highly contagious viruses might be synthesized by bioterrorists. The researchers responded that they were merely applying current knowledge and techniques to demonstrate the principle that viruses are basically chemical entities that can be synthesized in the laboratory. Do you think scientists should synthesize viruses or other agents that can cause infectious disease? What are the implications of forbidding such research?There have been recurring cases of mad-cow disease in the United Kingdom since the mid-1990s. Mad-cow disease is caused by a prion, an infectious particle that consists only of protein. In 1986, the media began reporting that cows all over England were dying from a mysterious disease. Initially, there was little interest in determining whether humans could be affected. For 10 years, the British government maintained that this unusual disease could not be transmitted to humans. However, in March 1996, the government did an about-face and announced that bovine spongiform encephalopathy (BSE), commonly known as mad-cow disease, can be transmitted to humans, where it is known as variant Creutzfeldt-Jakob disease (vCJD). As in cows, this disease eats away at the nervous system, destroying the brain and essentially turning it into a spongelike structure filled with holes. Victims experience dementia; confusion; loss of speech, sight, and hearing; convulsions; coma; and finally death. Prion diseases are always fatal, and there is no treatment. Precautionary measures taken in Britain to prevent this disease in humans may have begun too late. Many of the victims contracted it over a decade earlier, when the BSE epidemic began, and the incubation period is long (vCJD has an incubation period of 10 to 40 years). A recent study concluded that 1 in 2,000 people in Great Britain carry the abnormally folded protein that causes vCJD. In spite of these numbers, the death rate from vCJD remains low. It is not clear whether this means that the incubation period for the disease is much longer than previously thought, or whether they may never develop the disease. What measures have been taken to stop BSE?There have been recurring cases of mad-cow disease in the United Kingdom since the mid-1990s. Mad-cow disease is caused by a prion, an infectious particle that consists only of protein. In 1986, the media began reporting that cows all over England were dying from a mysterious disease. Initially, there was little interest in determining whether humans could be affected. For 10 years, the British government maintained that this unusual disease could not be transmitted to humans. However, in March 1996, the government did an about-face and announced that bovine spongiform encephalopathy (BSE), commonly known as mad-cow disease, can be transmitted to humans, where it is known as variant Creutzfeldt-Jakob disease (vCJD). As in cows, this disease eats away at the nervous system, destroying the brain and essentially turning it into a spongelike structure filled with holes. Victims experience dementia; confusion; loss of speech, sight, and hearing; convulsions; coma; and finally death. Prion diseases are always fatal, and there is no treatment. Precautionary measures taken in Britain to prevent this disease in humans may have begun too late. Many of the victims contracted it over a decade earlier, when the BSE epidemic began, and the incubation period is long (vCJD has an incubation period of 10 to 40 years). A recent study concluded that 1 in 2,000 people in Great Britain carry the abnormally folded protein that causes vCJD. In spite of these numbers, the death rate from vCJD remains low. It is not clear whether this means that the incubation period for the disease is much longer than previously thought, or whether they may never develop the disease. If you were traveling in Europe, would you eat beef? Give sound reasons why or why not.
- The genome of a retrovirus can integrate into the host cell genome. What gene is unique to retroviruses, and why is the protein encoded by this gene absolutely necessary for maintaining the retroviral life cycle?The coronavirus pandemic of 2020 is an example of a novel virus appearing in the global human population. A novel virus is a new virus: one that has been neither identified nor studied before.As a general rule, viruses are not considered to be alive based on several reasons. One such reason is that some viruses use RNA as their genetic material instead of DNA. Which of the five biological themes does this violate? Briefly explain why.