Derive an Equation that explains the realtionship between kE and kN with respect to the equilibrium constants provided in the reaction scheme provided below.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Derive an Equation that explains the realtionship between kE and
kN with respect to the equilibrium constants provided in the reaction scheme
provided below.
Assume that the enzyme must bind with A before it binds with B.
The two reactions are related by the following reaction scheme:provided below.
provided below.
A+B P
N =kN [A][B]
Assume that the enzyme must bind with A before it binds with B.
E+A+B EA+B EAB→ EP
E=KE [EAB]
The two reactions are related by the following reaction scheme:
K₁₁
E+ A + B
E + AB'
ΚΑ
Кт
EA + B
1
EAB
E + P
KB
KE
EAB*
EP
Transcribed Image Text:provided below. A+B P N =kN [A][B] Assume that the enzyme must bind with A before it binds with B. E+A+B EA+B EAB→ EP E=KE [EAB] The two reactions are related by the following reaction scheme: K₁₁ E+ A + B E + AB' ΚΑ Кт EA + B 1 EAB E + P KB KE EAB* EP
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