Describe the progression of cancer from an early benign lesion to a genetically heterogeneous malignant tumour and how this knowledge is used to design current and future antineoplastic treatments can you please give this in maximum detail as i am trying to understand this in extensive detail
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Describe the progression of cancer from an early benign lesion to a genetically heterogeneous malignant tumour and how this knowledge is used to design current and future antineoplastic treatments
can you please give this in maximum detail as i am trying to understand this in extensive detail
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- Surgery remains a mainstay in the treatment of many forms of cancer, but it is no longer used in diagnosis due to the risks associated with surgery and improved nonsurgical diagnostic methods. True FalseFor many years, targeted therapies for cancer treatment continue to be developed, however more and more patients are developing resistance to targeted therapies. Discuss one mechanism of resistance to targeted therapies for cancer and provide an example of how might creatively combat it using clinical concepts.Describe the progression of cancer from an early benign lesion to a genetically heterogeneous malignant tumour and how this knowledge is used to design current and future antineoplastic treatments
- Briefly summarize the conventional wisdom (DNA mutation theory) of the cause of cancer. Discuss the treatments and side effects of these treatments that are based on the DNA mutation theory.Can you critically evaluate this information including details in the discussion, also including molecular and cellular aspects as well as detailed diagnostic and treatment approach:- When tumours attempt to spread/invasive outside of their original tissue or to a remote metastatic location, they are said to be invasive. This process is typically started or sustained by the microenvironment around the tumour. Examine in-depth/Critically what a cancer microenvironment is and how it's considered to encourage tumour migration.Hello! My question is: Discuss the evidence used to establish the causal association between virus infection and cancer. How can this knowledge be used in the diagnosis, treatment and prevention of virus-associated tumours? Thank you!!!!
- Discuss why cancer treatment may involve a combinationof chemotherapy, radiation therapy, and surgery.1. Describe & explain the pathophysiology of cancer based on the diagram. Reference: https://www.onlinebiologynotes.com/cancer-etiology-pathophysiology-types-diagnosis-and- treatment/ Acquired (environmental) DNA damaging agents: • chemical • radiation viruses Activation of growth- promoting oncogenes NORMAL CELL DNA Damage Failure of DNA repair Mutations in the genome of somatic cells Alteration of genes that regulate apoptosis Malignant neoplasm / Successful DNA repair CANCER Inherited mutations: • Genes affecting DNA repair • Genes affecting cell growth Expression of altered gene products and loss of regulatory gene products Inactivation of cancer suppresor genes Clonal expansion Additional mutations (progression) T HeterogeneityName the six fundamental properties of malignant tumours. Which of these properties are amenable to study in a cell culture model of cancer and why?
- Invasiveness occurs in tumours when they are looking to spread through the tissue of origin or to a distant site of metastasis. This process is often triggered or maintained by the tumour microenvironment. Critically discuss what the tumour microenvironment is and how it is proposed to aid in tumour migration.A 56-year-old client was diagnosed with aggressive bone cancer that required a below the kneeamputation of the left leg 14 months ago. The client received recommended chemotherapy andradiation, but it was found recently that the cancer has metastasized to the chest and skull. There islymph node involvement with a primary tumor partially obstructing the right kidney. The client wasreadmitted 4 days ago for removal of the remaining portion of the left leg and was told that there is noappropriate surgical or medical intervention that would be beneficial at this point in the disease process.The interdisciplinary health care team has recommended palliative care upon discharge since the client’slife expectancy is between 3 and 5 months. The client has developed a mutually respectful relationshipwith a nurse on the unit who has provided care throughout all previous hospitalizations. The clientshares with the licensed practical nurse (LPN) that, “I have pills saved up and I’m going to commit…The most common therapeutic approaches to treating cancer include all of the following except ________. a. chemotherapy b. irradiation of tumors c. surgery to remove cancerous tissue d. administering doses of vitamins