To convert animal dose to human dose, the following formula may be applied: Human dose (m) = Animal dose mg (human weight\ animal weight) 2/3 d The following formula should be used to calculate the incremental risk (Pexcess) at a given dose: Pdose - Pcontrol Pexcess 1 - Pcontrol where Pcontrol is the risk at zero dose of the chemical. The average female mice weight is assumed 0.05kg. Dose in female mice % with liver cancer mg/d 0.00 2.6 0.08 4.9 0.15 9.6 0.20 11.7 0.30 16.4 0.38 20.1 0.45 22.6
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- 22:23 1O 000 · 11:24 A9 OB1 r ll l 52% . +964 782 734 3923 2m541139927815107... Patient Encounter Part 3 The pretreatment workup is summarized below. Pathology: 47-year-old female with new diagnosis of infiltrating intraductal adenocarcinoma involving the left breast and regional node. Further tests on tumor samples indicated ER (8%), PR (negative), HER2 (negative), Ki-67 (72%), and grade (poorly differentiated). Intrinsic subtype (luminal B, HER2-negative). Radiology: FDG-PET/CT indicated a 5.3 x 2.5 cm mass in the left breast which appeared to extend to the epidermis of the skin; one node in the left axilla was also involved with tumor. No other evidence of distant disease was visualized. Laboratory: CBC, liver, and kidney function tests WNL, alkaline phosphatase and calcium are normal also. Stage: IB (T, N, M,) List the most important prognostic factors in this patient with newly diagnosed breast cancer. Assess the patient's level of risk for relapse. 50 SECTION 16 | ONCOLOGIC…41% E 22:31 ... PHC213_2019_06_F.pdf 4. Which of the following statement best describes a goal of therapy: A. Cure the infection B. Prevent flu with a flu vaccine C. Reduce pain from 8 to 4 (on a scale from 0-10) within 48 hours with paracetamol D. Prevent the progression of kidney disease 2 5. The following statement best describes the pharmaceutical care process: A. Develop a relationship → Identify medicine-related problems → Development of care plan & implementation → Assessment -→ Follow-up B. Develop a relationship → Identify medicine-related problems → Assessment → Development of care plan & implementation → Follow-up C. Develop a relationship → Assessment → Identify medicine-related problems → Development of care plan & implementation → Follow-up D. Develop a relationship → Assessment → Development & implementation of care plan> Identify medicine-related problems → Follow-up 6. You review a prescription where paracetamol is prescribed as 1g, 4 hourly (recommended 1g 6 hourly).…Aoy i 23 ~OY4207= il < Jlgudl = AST is widely distributed throughout the body with the highest activity in the heart. False O True O dilayl haa
- -t=449595&cmid=1668389 textb... My ATI NOLOGY SUPPORT ✓ MTH 208-01 (MW... K Kaplan Login WP WileyPLUS VitalSource Books... Zika virus is chiefly spread using an insect vector, more specifically, mosquitoes. Given this, which of the following helps account for why all blood donations in J.S. are screened for Zika? O a. Zika can be easily transmitted from person to person even through incidental contact O b. Zika infections are now common and regularly reported in every U.S. State (except Alaska) O c. Screening of blood donations is the main way in which Zika infections are diagnosed in the U.S. O d. Climate change extends the habitat of mosquitoes that can carry the virus Next page- Einstein X Case Studies.doc + er?url=https://wheatland.orbundsis.com/einstein-freshair/Videos/0216D9403D0ED43358766A676D8A4817/Case+Studies.doc 2KMTCentral | NBA... a Amazon.com: Onlin... Beyond The Lights... (6) The Reason Why... Isaiah Blames Zora... Wato Open with Case Study, Chapter 23, The Hematologic and Lymphatic Systems Michael Allen is a 25-year-old male cancer client who is currently undergoing multiple rounds of chemotherapy. His chemotherapy treatment has caused him to have abnormally low amounts of erythrocytes, leukocytes and thrombocytes. His hospitalization treatment orders include being placed in protective isolation and receiving blood transfusions of packed red blood cells. In order to prepare for the transfusion, the lab draws a blood sample for a type and crossmatch. Michael's blood type is identified as O+. (Learning Objectives 3, 4, 5, 6) 1. What types of blood could this client receive? Is his blood type the most advantageous blood type for receiving blood…41% E 22:30 K PHC213_2019_06_F.pdf 1. Mr Jansen is diagnosed with pneumonia and is not receiving any antibiotic therapy. His medication related problem can be described as: A. Adverse drug reaction B. Non-adherence C. Receiving unnecessary therapy D. Requires additional therapy 2. Mrs June is not taking her cholesterol medicine as it causes muscle aches. Her medication related need may be classified as: A. Adherence B. Effectiveness C. Indication D. Safety 3. Mr Jack's infection is not currently responding to the current antibiotic regimen. His medication related need may be classified as: A. Adherence B. Effectiveness C. Indication D. Safety 4. Which of the following statement best describes a goal of therapy: A. Cure the infection B. Prevent flu with a flu vaccine C. Reduce pain from 8 to 4 (on a scale from 0-10) within 48 hours with paracetamol D. Prevent the progression of kidney disease 5. The following statement best describes the pharmaceutical care process: + A. Develop a…
- Mr. Mitch Igan, 60YOM, had a CVA. He is NPO and a NGT was placed. IVF are at 75 mL/hr. • Height is 5 feet 6 inches = 66 inches = 167.64 cm = 1.7 m • Current weight = 143 lbs = IBW 142 lbs = 64.5 kg • BMI = 23.1 65 kg • Estimated kcal needs = 1625 to 1825 kcal/day (25 to 28 kcal/kg) .Estimated protein needs = 73 to 83 grams protein/day (1.2 gm/kg) • Estimated fluid needs = 1850 to 2050 mL/day (30 ml/kg) You receive a consult for EN recommendations. You decide to use Jevity 1.2: 18 gm fiber/L 1.2 kcal/mL 80.7% free water 55.5 gm protein/L 169.4 gm CHO/L 39.3 gm fat/L 100% RDIs for vitamins met with 1000 mL/day one carton contains 240 mL a) What is your recommendation for the hourly rate (mL/hr) of Jevity 1.2? b) What is the goal volume in liters (to two decimal places)? c) How many kcal will the goal volume provide? How many kcal/kg? d) How many grams of protein will the goal volume provide? How many gm/kg?Based on the image below, select the correct statement. Complex II QH₂ Q- 10 2 HO 2 HO Fe-S (2.8 FADH₂ FAD- Succinate Fumarate https://canvas.uts.edu.au/assessment questions/356986/files/1562694/download? 2e verifier-eUTT3hYal2YYTWlywV8TIFA3USmzCsM52jECmvTo O Succinate is reduced to fumarate O Succinate is oxidised to FAD O The Fe-S center shuffles electrons from FAD to ubiquinone (Q) O The Fe-S center shuffles electrons from FADH2 to ubiquinone (Q) The Fe-S center shuffles electrons from FADH2 to ubiquinonol (QH2) W 88 16°CIn a placebo-controlled study, 10 healthy subjects were given oral triazolam 0.5 mg before and after rifampicin 600 mg daily for 5 days. Rifampicin reduced the triazolam AUC by 95% and decreased its maximum plasma levels by 88%, when compared with placebo. The elimination half-life was reduced from 2.8 hours to 1.3 hours. Pharmacodynamic tests (drowsiness, sway, Maddox wing, etc.) showed that rifampicin abolished the effects of triazolam.a) Why is the AUC of triazolam reduced in the presence of rifampicin? b) Given the above scenario, if you were to accommodate this situation by dosage adjustment strategies, in the presence rifampicin what dose of triazolam would you have recommended, keeping dosage interval the same as when there was no rifampicin? answer part b
- Based on the 2017 American Heart Association Diet and Lifestyle Recommendations, describe three strategies that could help an individual in reducing cardiovascular disease risk.Average Systolic reading (mm Hg) Average Systolic reading (mm Hg) "Dark Chocolate A" "Dark Chocolate B" 117 110 According to the average results, it appears that Dark Chocolate B is more effective. Based on this limited amount of information, though, several questions should come to mind regarding the experimental design/make-up of these two experimental groups before you blindly accept Chocolate B's effectiveness. Below, list three things you would like to know about these experimental groups that would assist you in comparing the above values and evaluating the chocolate's effectiveness. (more than 3 things is,of course, acceptable) PREP 1. 2. 3.The recommended dose range of intravenous gentamicin for an adult is 1 to 1.7 mg/kg q8h. Calculate the daily dosage range in mg, for Mr. K weighing 154 lb.