Answered: Draw a titration curve for the…

Draw a titration curve for the tetrapeptide Trp-Asp-Lys-Gly. Label all pK,s, the pl and the net molecular charges at pH 1 and pH 14 on the graph with their values.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins

Section26.SE: Something Extra

Problem 50AP: The -helical parts of myoglobin and other proteins stop whenever a proline residue is encountered in...

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4) Draw a titration curve for the tetrapeptide Trp-Asp-Lys-Gly. Label all pK,s, the pl and the net
molecular charges at pH 1 and pH 14 on the graph with their values.

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Given tetrapeptide:

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Structural representation

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Determination of pI

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Determination of pI (continued)

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Determination of pI (continued)

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Determining charge at pH 1

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Determining charge at pH 14

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Titration curve

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