Answered: Following is a synthesis for the…

Following is a synthesis for the antiarrhythmic drug bidisomide. The symbol Bn is an abbreviation for the benzyl group, C,H,CH,– 1. NANH, 1. NANH, H,SO, Bn CN 2. CN CN CI Bn A B C

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter23: Carbonyl Condensation Reactions

Section23.SE: Something Extra

Problem 35MP: Isoleucine, another of the twenty amino acids found in proteins, is metabolized by a pathway that...

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Question

Propose mechanisms for the conversion of A to B and of B to C. What is the function of sodium amide in each reaction?

Following is a synthesis for the antiarrhythmic drug bidisomide. The symbol Bn is an
abbreviation for the benzyl group, C,H,CH,–
1. NANH,
1. NANH,
H,SO,
Bn
CN
2.
CN
CN
CI
Bn
A
B
C

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