HO benzene arene oxide phenol 1 1

General, Organic, and Biological Chemistry
7th Edition
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:H. Stephen Stoker
Chapter14: Alcohols, Phenols And Ethers
Section: Chapter Questions
Problem 14.108EP
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Hydrocarbons like benzene are metabolized in the body to arene oxides, which rearrange to form phenols. This is an example of a general process in the body, in which an unwanted compound (benzene) is converted to a more water-soluble derivative called a metabolite, so that it can be excreted more readily from the body.

a.) Classify each of these reactions as oxidation, reduction, or neither.
b.) Explain why phenol is more water soluble than benzene. This means that phenol dissolves in urine, which is largely water, to a greater extent than benzene

HO
benzene
arene oxide
phenol
1
1
Transcribed Image Text:HO benzene arene oxide phenol 1 1
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