In a two factor cross, the longest possible map distance is 50 map units. Explain why this is true. How then can genetic maps show two genes that are 70 map units or more apart?
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- In a two factor cross, the longest possible map distance is 50 map units.
- Explain why this is true.
- How then can genetic maps show two genes that are 70 map units or more apart?
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- To determine the recombination frequency between body color and wing genes in flies, you perform several crosses where you cross an F1 having red body and smooth wings with a yellow-bodied, crinkle-winged fly. You get the following results. What is the distance between the genes for body color and wing surface in map units?If d and f = 2%, what is the correct arrangement of the genes d,e,f?The alleles his-5 and lys-1, found in yeast, result in cells that require histidine and lysine for growth, respectively. A cross was made between two haploid yeast strains that are his-5 lys-1 and his+ lys+. 973 tetrads were analyzed, with the following pattern: 7 tetrads with 2 his-5 lys+ spores and 2 his+ lys-1 spores 603 tetrads with 2 his-5 lys-1 spores and 2 his+ lys+ spores 363 tetrads with 1 his-5 lys-1 spore, 1 his-5 lys+ spore, 1 his+ lys-1 spores, and 1 his+ lys+ spore Compute the map distance between these two genes using the method that considered double crossovers and the one that does not. Show your work. Which give the higher value? Why? What is the frequency of single crossovers between these genes? Explain. Based on the frequency of single-crossovers, how many double crossovers would one expect? Is positive interference occurring?
- his-l and lys-3 are alleles found in baker's yeast that require histidine and lysine for growth, respectively. A cross was made between two haploid yeasts that are his-1 lys-3 and his lys". From the analysis of 900 individual tetrads, the following numbers of tetrads were obtained: GI: 2 spores are his-1 lys* +2 spores are his* lys-3 = 8 G2: 2 spores are his-1 lys-3+ 2 spores are his* lys* = 512 G3: 1 spore is his-1 lys-3 +1 spore is his-1 lys + 1 spore is his lys-3+ 1 spore is his" lys = 380 (i) Name the ascus type of each group as P, NP or T. (ii) Are the genes linked? Explain your answer. (iii) If the genes are linked, calculate the distance between the genes.The alleles his-5 and lys-1, found in yeast, result in cells that require histidine and lysine for growth, respectively. A cross was made between two haploid yeast strains that are his-5 lys-1 and his+ lys+. 973 tetrads were analyzed, with the follow pattern: 7 tetrads with 2 his-5 lys+ spores and 2 his+ lys-1 spores 603 tetrads with 2 his-5 lys-1 spores and 2 his+ lys+ spores 363 tetrads with 1 his-5 lys-1 spore, 1 his-5 lys+ spore, 1 his+ lys-1 spores, and 1 his+ lys+ spore Compute the map distance between these two genes using the method that considered double crossovers and the one that does not. Which gives the higher value? Why? What is the frequency of single crossovers between these genes? Explain. Based on the frequency of single-crossovers, how many double crossovers would one expect? Is positive interference occurring?The alleles his-5 and lys-1, found in yeast, result in cells that require histidine and lysine for growth, respectively. A cross was made between two haploid yeast strains that are his-5 lys-1 and his+ lys+. 973 tetrads were analyzed, with the follow pattern: 7 tetrads with 2 his-5 lys+ spores and 2 his+ lys-1 spores 603 tetrads with 2 his-5 lys-1 spores and 2 his+ lys+ spores 363 tetrads with 1 his-5 lys-1 spore, 1 his-5 lys+ spore, 1 his+ lys-1 spores, and 1 his+ lys+ spore Compute the map distance between these two genes using the method that considered double crossovers and the one that does not. Show your work. Which give the higher value? Why? What is the frequency of single crossovers between these genes? Explain. Based on the frequency of single-crossovers, how many double crossovers would one expect? Is positive interference occurring?
- In an intra-species cross performed in mustard plants of two different species (Brassica juncea and Brassica oleracea), a tall plant (TT) was crossed with a dwarf (tt) variety in each of the two species. The members of the F1 generation were crossed to produce the F2 generation. Of the F2 plants, Brassica juncea had 60 tall and 20 dwarf plants, while Brassica oleracea had 100 tall and 20 dwarf plants. Use chi-square analysis to analyze these results.In a tetraploid B /B /b /b, how many quadrivalent possiblepairings are there? Draw them (see Figure 17-5).The following is a linkage map of chromosome 5 for three genes in tomato: (see image) The cross between the triple heterozygote (Lf J W/ lf j w) and a triple homozygous recessive produced 500 progeny. Assume that there is no interference in the Lf-W region. Give the expected number of individuals for each of the following progeny types and show complete solutions.a. with crossover in the Lf-J and J-W regionsb. with crossover in the Lf-J regionc. with crossover in the J-W regiond. without crossover in the Lf-W region
- In a cross between mice the genotypes AB/ab ab/ab, what is the recombination frequency if the progeny numbers are 72 AB/ab, 68 ab/ab, 17 Ab/ab, and 21 aB/ab? The alleles are shown for each chromosome, separated by a slash (/).Genes A, B, and C lie at map positions 2.5, 7.5, and 17.5, respectively. In a three-point test cross, you observed 2 double crossovers in a total of 1000 progeny. What is the interference in this region?A series of three-point testcrosses is made to determine the genetic map order of seven linked allele pairs: A/a, B/b, G/g, H/h, Q/q, R/r, and Y/y.From each cross between a triply heterozygous parent listed below, two recombinant classes were noticed as the least frequent among all 8 progeny classes, and are listed at the right in the table. A. For each testcross write the genotype of the F1 heterozygous parent. F1 Parental Phenotype Least frequent F2 Phenotype 1.AHB&ahb AHb & ahB 2.RYh&ryH RYH & ryh 3.BhY&bHy Bhy & bHY 4.qYB&Qyb qYb & QyB 5.AbQ&aBq Abq & aBQ 6.ghR&GHr ghr & GHR B. Write the unified map order of these genes, showing your reasoning.