Mark as true or false the statements about amino acid reactivity and peptide synthesis: ( ) Peptides are very diverse in terms of their function/application. Some are hormones or their releasing factors, some are neurotransmitters, some are toxins, some are natural antibiotics, and some work as sweeteners, such as aspartame. ( ) Most of the natural peptides occur in low concentration, which makes their isolation from the matrix difficult, and therefore, their chemical synthesis is necessary. ( ) The chemical synthesis of peptides is only done with the use of enzymes ( ) A difficulty in the synthesis of peptides is due to the fact that carboxylic acids and primary or secondary amines do not form amide bonds easily. When mixing the two, what we would have would be products from the transfer of protons between them, forming a charged species. ( ) The chemical synthesis of peptides uses a chemical reagent to activate the carboxylic acid of the amino acid, which will undergo nucleophilic attack from the amino group (NH2) of another amino acid, resulting in the formation of the peptide bond between them
Mark as true or false the statements about amino acid reactivity and peptide synthesis:
( ) Peptides are very diverse in terms of their function/application. Some are hormones or their releasing factors, some are neurotransmitters, some are toxins, some are natural antibiotics, and some work as sweeteners, such as aspartame.
( ) Most of the natural peptides occur in low concentration, which makes their isolation from the matrix difficult, and therefore, their chemical synthesis is necessary.
( ) The chemical synthesis of peptides is only done with the use of enzymes
( ) A difficulty in the synthesis of peptides is due to the fact that carboxylic acids and primary or secondary
( ) The chemical synthesis of peptides uses a chemical reagent to activate the
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