Mendel's work was ignored for about 35 years, until it was essentially replicated. Meanwhile, cell biologists worked out the details of meiosis and mitosis to try to understand inheritance. True False
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25) Mendel's work was ignored for about 35 years, until it was essentially replicated. Meanwhile, cell biologists worked out the details of meiosis and mitosis to try to understand inheritance.
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- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?Part 1: Make a three part process drawing (like a cartoon strip) to demonstrate Mendel's Principle of Segregation. Use two parents with homologous chromosomes marked with alleles "A" and "a". Circle and label these three action parts of the Principle of Segregation: a) parents are diploid, b) alleles separate to form haploid gametes (indicate when this happens), and c) gametes from each parent combine at random to form diploid offspring Part 2: Use the cross Aa x Aa and a Punnett square to demonstrate Mendel's Principle of Segregation. Circle and label these three action parts of the Principle of Segregation: a) parents are diploid, b) alleles separate to form haploid gametes and c) gametes from each parent combine at random to form diploid offspring. Part 3: Use homologous chromosomes marked with alleles "A" and "a" and a second pair of homologs marked with alleles "B" and "b". to demonstrate Mendel's Principle of Independent Assortment in cells in Meiosis. Indicate what phase this…
- Part 1: Make a three part process drawing (like a cartoon strip) to demonstrate Mendel’s Principle of Segregation. Use two parents with homologous chromosomes marked with alleles “A” and “a”. Circle and label these three action parts of the Principle of Segregation: a) parents are diploid, b) alleles separate to form haploid gametes (indicate when this happens), and c) gametes from each parent combine at random to form diploid offspring Part 2: Use the cross Aa x Aa and a Punnett square to demonstrate Mendel’s Principle of Segregation. Circle and label these three action parts of the Principle of Segregation: a) parents are diploid, b) alleles separate to form haploid gametes and c) gametes from each parent combine at random to form diploid offspring. Write the expected genotypic and phenotypic ratios.A couple enters your genetic counseling clinic for some family planning advice. The woman’s father was color blind, but her own vision is normal. The man has no family history of color blindness. Neither the man nor woman have any known history of hemophilia, but their first child (a boy) has hemophilia. They ask you to calculate the chance that their nextchild will be affected by one or both conditions. You remember from your genetics training that these are both X-linked recessive conditions and that they are closely linked: in fact, their genetic loci are separated by only 10cM! During the interview with this couple, you draw the following pedigree to represent their information. Given what you know, determine for this couple what chance they have of each of the following (in the table).Chromosome theory is instrumental in ensuring Mendel’s work, why?
- B B BB Bb b Bb bb Brown rabbits have the genotype BB or Bb. White rabbits have the genotype bb. If two brown rabbits, with the genotypes seen in the Punnett square above, have baby rabbits, what is the probability that the baby rabbits will also be brown? A B) 50% 75% D) 100% 5) According to Mendel's is why gametes have half the usual number of chromosomes. one copy of a gene is passed randomly from each parent to their offspring. This Sign out acerAn individual comes into your genetics clinic to be tested for any anomalies. When looking at their karyotype, you notice they have three X chromosomes and a Y chromosome. What information would you be able to relay to this individual? O They have Turner syndrome, are genetically female, and have two Barr bodies per cell. O They have Klinefelter syndrome, are genetically female, and have two Barr bodies per cell. O They have Klinefelter syndrome, are genetically male, and have two Barr bodies per cell. O They have Klinefelter syndrome, are genetically male, and have three Barr bodies per cell. O They have Turner syndrome, are genetically male, and have three Barr bodies per cell.In pre-DNA fingerprint days, blood type was often used in paternity disputes to exclude possible fathers. If the man in question has type B blood, and the child has type A blood, and the mother has type AB blood, can the man be the father of the child? Group of answer choices Yes, but only if he is homozygous for the B allele No Yes, but only if he is heterozygous for the B allele Yes, but only if both of his parents were Type AB
- This pedigree (Pedigree #2) illustrates the inheritance of a simple Mendelian trait. If individuals III- 5 and III-6 have children, what are the chances that the children would have this disorder? 0% 1/4 2/3 O 1/6 ㅇㅁTwo mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is afflicted with hemophilia, a disease caused by an X-linked recessive allele. Neither parent has the disease. Mother 2 has a normal son, despite the fact that the father has hemophilia. Several years later, couple 1 sues the hospital, claiming that these two newborns were swapped in the nursery following their birth. As a genetic counselor, you are called to testify. What information can you provide the jury concerning the allegation?You do an experiment with the genetics of plant flower color. You cross a red flowered plant with a yellow flowered plant. The F1 progeny from the hundreds of seeds produced include plants that had red flowers and others with yellow flowers but there are also many plants whose flowers were a wide variety of shades of orange in-between the two extremes (that is not just one color halfway between the parents). What kind of non-Mendelian inheritance can lead to this type of result? Explain.