What is the expected product A for the following crossed aldol reaction? Note, formation of the enolate is carried out under irreversible conditions.1. LDA, THF, -78 °CH3C.CH3H.3. H,O工2.

Answered: Image /qna-images/answer/32bdf9e7-489a-44f7-8e32-bf1c365a3067.jpg

Answered: Nole, formatión of the enolate is…

Science

Chemistry

Nole, formatión of the enolate is carried out under irreversible conditions. 1. LDA, THF, -78 °C H3C. CH3 2. H 3. Н.О

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter14: Elimination

Section: Chapter Questions

Problem 8CTQ

See similar textbooks

Related questions

Q: 1. Calculate the [OH` ] (aq) in a solution in which [ H'] = 3 x 10*M

A: Given that [H]+ = 3 X 10-5 M

Q: In initial steps of the sol-gel process, a reactive metal is treated with an alcohol to form a metal…

Q: NaBH, H+ agua CH,OH H,0 H+ Ag,0 1) H+ 2) NH, OH-

A: In this question, we will draw the products for all reaction by using mechanism and intermediate…

Q: Propose a structure for an aromatic hydrocarbon, C3H10, that can form three C3HgBr products on…

A: The molecular formula of the aromatic hydrocarbon given is C8H10.

Q: What reactants are expected to afford the following Diels-Alder adduct? H3C H. D. DIOT C

A: Here we are required to find the diene and dienophile required for Diels Alder adduct

Q: 6. What is the coefficient of the species that will be in the greatest amount if there are 12.5…

A: Given, 12.5 mol of sodium oxalate reacted with 12.5 moles of potassium permanganate.

Q: A chemistry graduate student is studying the rate of this reaction: 2C1,0, (8) → 2C1, (g)+50, (g) He…

Q: this is incorrect, I entered that number and it marked it as wrong

Q: NES.pdf + File |…

A: The naming of an organic compound can be done with help of rules of international union of pure and…

Q: Can you please indicate the ion flow for the image I posted below

A: Here we are required to find the direction of flow of electron in the electrochemical cell

Q: oues- ow mamy moles of HCI ane in 53.4mL of a L.ll M HeL solution 2

Q: Which of the following statements accurately describes the difference be ctrolytic cells? A. The…

A: Redox reaction are those in which both oxidation and reduction reaction occurs simultaneously.

Q: 4. Which of the following statements accurately describes the difference between galvanic and…

A: Redox reaction are those in which both oxidation and reduction reaction occurs simultaneously.

Q: Contrary to legend, camels do not store water in their humps, which consist of large fat deposits.…

A: It is known that tripalmitoylglycerol is made up of three palmitoyl-CoA molecules. Therefore we have…

Q: 13. A conclusion from Faraday's second law is that for a given quantity of electricity, the moles of…

A: Answer - c. decreases That is , A conclusion from Faraday's second law is that for a given quantity…

Q: A. Hydrolysis Observations Sample Warming effect Reaction with 2% Reaction with sat'd. AGNO, NaHCO,…

A: Hydrolysis of different-different sample and to write observation of it (Warming effect , Rxn with…

Q: The concentration of Br" in a sample of seawater is 8.3 x 104 M. If a liter of seawater has a mass…

A: ppm of Bromine ions in sea water is equal to grams of Bromine ions in 1000000 grams of sea water.

Q: Hello, can you please figure out the net-ionic equation too, please.

A: The acid-base nature of the salt solution depends on the nature of the acid and base from which the…

Q: [References] Use the References to access important values if needed for this question. Consider the…

A: Given, NH4NO3(aq) ➝ N2O(g) + 2H2O(l) Standard entropies at 298 K are, NH4NO3(aq) = 259.8 J/mol.K…

Q: What is more stable in the newman projection a & b?

A: Stability is dependent on steric hindrance .

Q: Compare the two quantities based on the given condition: At the equivalence point in the titration…

A: At the equivalence point, all of the Ca2+(aq) is converted to CaY2-(aq).

Q: 3. Indicate whether each of the following solutions is acidic, basic or neutral. a) [H*] = 2.0x104…

A: Acidic , basic , neutral solution can be explained using pH value . If the value of pH is less than…

Q: 16. Which of the following statements is FALSE? A. Oxidation and reduction half-reactions occur at…

Q: Question 17 For the following coordinmtion complu{Fe (C.0.XH,0),3' name Determine the geometry Gire…

Q: Consider the titration of 100.0 mL of 0.200 M HONH2 by 0.100 M HCl (Kb for HONH2 = 1.1 x 10-8)? (…

Q: MnO aq) + 2+ + C20laq) → COri) + Mn) А. 2 В. 5 С. 10 D. 16 Е. 15

A: The coefficient of a compound can be determined from the balanced chemical reaction. A reaction will…

Q: (0 10. What is the purpose of the salt bridge in a voltaic cell? A. It blocks the flow of electrons…

Q: In Filkenstein test, the reaction is driven by the precipitation of the NaCl or NaBr in the acetone…

A: Filkenstein test or reaction is a bimolecular substitution reaction (SN2) reaction where one halide…

Q: Question 15 For the reaction 2CHCI30 tOz19)→2coe b)2HC/01(AG= -452.4K) at 25°C when (CHCI) =3.2…

A: Here we are required to find whether the reaction given is spontaneous or non spontaneous.

Q: 2. molecular equation NaPO, + FeCl, → net ionic equation 3. molecular equation Me(ОН), + СаCl,— net…

A: We would use solubility rules to predict if any solid compound will form , so accordingly we need to…

Q: Question For the following coordinction (omples:(Co (H,0), CIB-3 Give the name Determine the…

Q: metals will displace hydrogen gas out of acid?

Q: Draw the diastereoisomers and optical isomers of dichloridobis(ethylenediamine)chromium (III). Label…

A: Diastereoisomers are not the mirror image of the compound but have the same molecular formula, and…

Q: 3. Collect at least 5 examples of cells working under Redox principles. 4. Write down all chemical…

A: Redox reaction occur spontaneously in galvanic cell.

Q: 24. Electrochemical cell potentials can be used to detemine equilibrium constants that would be…

Q: Hydrogen gas (H2) reacts with oxygen gas (O2) to form liquid water (H2O). Student A writes the…

Q: 2. Calculate the [ H*] of each of the following given the pH and pOH c) pOH = 2.5

Q: Answer the following chemical reaction 1. Iron reacts with oxygen gas and forms solid iron(II)…

A: Reactants are the substances which are present at the start of any reaction. Products are the…

Q: grams of aspirin tablets are dissolved in water and titrated with the NaOH from an initial volume of…

Q: Draw a Lewis structure for SiF5- and answer the following questions based on your drawing.

A: Draw a Lewis structure for SiF5- and answer the following questions based on your drawing.

Q: Discuss the solubility behaviour of polymers from a thermodynamic point of view. What is the…

A: thermodynamics of solubility of polymers :

Q: 28. For the following reaction, all of the reactants and products are in their standard…

Q: 277 10. (a) It may be possible for the isotope of meitnerium 10Mt to undergo spontaneous fission…

A: a.) First we need to write a balanced reaction for fission. Then we can calculate energy released.…

Q: Which statement describes the trend of ionization energy in the periodic table? 19. (a) increases…

Q: What is the product? OCH3 1. DMSO, (CICO)2 HO, 2. EtgN, CH,Cl, CH, CH.

Q: 1. Which of the following statements accurately describes the Nemst equation shown below? Ecell =…

A: Redox reaction are those in which both oxidation and reduction reaction occurs simultaneously.

Q: A 0.7120 g specimen of iron was brought into solution and passed through the Jones redactor.…

A: Given , Mass of iron ore sample = 0.7120g Volume of KMnO4 used = 39.20mL Normal concentration of…

Q: What volume in liters is occupied by 39.1 g of C2H2 at 445 mm Hg and 46° C?

A: Given, The volume in liters is occupied by 39.1 g of C2H2 at 445 mm Hg and 46° C is:

Q: Calculate the average rate using the graph below. 1.2 1.0 0.8 [HO 0.6 0.4 0.2 10 20 30 40 50 60 70…

A: To calculate the average rate of the reaction.

Q: र १ज१A CName functional gooup tyboidization ार्वाचवकोमल bond शिकहुनीक order tength Pofवि० potarsity.…

Concept explainers

Diol

In chemistry there are so many chemical compounds that have a hydroxyl group but a chemical compound having two hydroxyl groups (-OH) is termed as a diol. It also implies the presence of two alcohols whereas polyols contain two or more than two hydroxyl groups (-OH). Glycol or 1,2-diol is an aliphatic diol that has two alcohol groups on adjacent carbon atoms. In industries, the most commonly used diol is ethylene glycol.

Question

What is the expected product A for the following crossed aldol reaction? Note, formation of the enolate is carried out under irreversible conditions.
1. LDA, THF, -78 °C
H3C.
CH3
H.
3. H,O
工
2.

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Follow-up Questions

Read through expert solutions to related follow-up questions below.

Follow-up Question

i dont see the final product as an answer choice on my homework

Solution

by Bartleby Expert

SEE SOLUTION

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

resource from Cengage Learning - Google Chrome ssignment/takeCovalentActivity.do?locator=assignment-take e by the Aldol Condensation (References) OH base + H,0 heat H. H3C H. The aldol reaction is a carbonyl condensation reaction between two carbonyl partners and involves a combination of nucleophilic addition and a-substitution steps. One partner is converted into an enolate ion nucleophile and adds to the electrophilic carbonyl group of the second partner. In the classic aldol reaction, the carbonyl partners are aldehydes or ketones, although aldehydes are more reactive. The product is a B-hydroxy carbonyl compound. In the mixed aldol reaction, the best results are obtained when one of the partners does not have an a-hydrogen. It cannot form an enolate anion and can therefore not undergo self-reaction. The enolizable aldehyde is added slowly to a basic solution of the first aldehyde so that the mixed product is preferentially formed. Under reaction conditions slightly more vigorous…
1. Provide structures for the products and/or starting materials for the following reactions. Donor Acceptor NaOH CH₂CH₂OH heat loss of H₂O H3C mixed-aldol condensation product NaOH CH₂OH heat *) NOE EtOH #40 2) H₂O* ΕΙΟ CH₂ mixed-Claisen condensation product +HgC. H3C CHS H loss of H₂O mixed-aldol condensation product H3C людете CH3 NaOEt loss of H₂O intramolecular aldol condenstation cyclization product
Provide the missing intermediates and final product in the following synthesis. 1. LDA (excess). A 2. Н,о Br2 1. NaH В 2. C H,/Pd CI4 Lindlar catalyst ВА 1. CH,MgBr H,CrO4 D E 2. NH,CI, H,O F G
1. Reactions. Ch0ose 5. Identify (draw the structure showing stereochemistry when required) the major product required to complete the following transformations. NaOH A NaOH B NaOH 2 H (note the 2 equivalents of the aldehyde) D 1.NaOEt 2. H,0* 1.NaOEt 2. H,0* F
4) When a mixture of two different compounds both containing a hydrogens are placed under acidic or basic conditions, crossed aldol products can be formed. By either self-condensation or cross condensations. Draw the 4 aldol and 4 a.B-unsaturated ketones that can be made from the following mixed system. -OH 4 products One way to control this is by either having only one compound with a hydrogens or by reacting the desired nucleophile with lithium diisopropylamide (LDA) before addition of second carbonyl. The issue here is that this reaction stops at the aldol unless excess base is used. он LDA OH heat Show a synthetic scheme of how to use the following carbonyls to control the formation of each cross product (i.e. each as nucleophile and electrophile, two reactions). and
Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction. CH3 CH3 H dilute NaOH 95% aq. ethanol, 0-5⁰ You do not have to consider stereochemistry. • If no reaction occurs, draw the organic starting material. O-Sn [F ? ChemDoodleⓇ
Which reaction (s) does an anhydride produce? HO. NEl3 CI КОН I. calor OK II NH2 O. IV HO HO. calor III a. Ob., IV Oc. I, II d., II, III, IV
Identify the best reagents to complete the following reaction. 1. NaOH A 2. CH3CH2CH2NH2 1. HCI В 2. CH3CH2CH2NH2 ОН CH3CH2CH2NH2 C 1. SOCI2 D 2. CH3CH2CH2NH2 1. CH3CH2CH2NH2 E 2. SOCI2 NH,
The reaction below is a base-catalyzed aldol reaction. O || CH₂-C-H CH3-C-H Ethanal (Acetaldehyde) H I CH3-C-H Ethanal (Acetaldehyde) NaOH Draw curved arrows to show the movement of electrons in the step of the mechanism shown below. Arrow-pushing Instructions AC⇒x= :O: || :CH₂-C-H OH Bl CH3-CH—CH2-CH -CH₂-1-1 a 3-Hydroxybutanal (B-hydroxyaldehyde; formed as a racemic mixture) :0: :0: || CH3—CH—CH2-C-H A tetrahedral carbonyl addition intermediate X
4.Which is the most thermodynamically stable product of the following aldol condensation reaction? NaOH H. Me `Me EtOH а. Е, Z b. Е, E с. Z, E d. Z,Z
Drag and drop the reagents needed for each step of the following synthesis. 1. HO, 2. A Brz. NAOH (ag) B) Socl2 c) CH;CO,Na H30* E CH3CO2H F N2OH, H,O
Draw the structure for the major reaction product for the following reactions. Draw out the mechanism. 1. SPh₂BF4 KOH, DMSO 2. LDA, THF, -78 °C 3. H+, H₂O C