Urgently needed omozygo25. Phenylketonuria (PKU), which is caused by a recessive mutation, occurs at the rate of about 1 in 10,000 people inNorth America. What is the allele frequency for the allele causing the disease and what is the frequency of heterozygouscarriers of the allele in the population of North America? Assume Hardy-Weinberg equilibrium.Frequency of PKUA)1/125B)1/250C)1/50D)1/125E)1/100Frequency ofheterozygote carriers1/621/1251/1001/2501/5026. HER2, SRC, RAS and MYC are all genes which are implicated in a variety of cancers. Which of the following is not aclassification which can be used for any of these genes?A) Receptor tyrosine kinaseB) Intracellular tyrosine kinaseC) Transcription factorD) Intracellular secondary signal moleculeE) Non-receptor tyrosine kinase

Approach to solving the question: Detailed explanation: Examples: Key references:

Answered: omozygo 25. Phenylketonuria (PKU),…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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.. Nowadays, newborn babies are required to be tested for phynylketonuria (PKU), an autosomal recessive genetic disorder. If untreated, individual homozygous for PKU suffer mental retardation. In a recent year, 4 PKU babies were detected out of 126,000 tested. Assuming Hardy-Weinberg conditions, what is the frequency of the PKU gene in this population (Give your answer in decimal number with 3 decimal places)?
63. In an isolated population, a single mutation allele of the cystic fibrosis transmembrane regulator (CFTR) gene is present at a frequency of 0.1. The normal CFTR allele and the mutation allele are in Hardy-Weinberg equilibrium in this population. Which of the following is the approximate frequency of homozygosity for the normal CFTR allele in this population? A) 0 OB) 0.01 C) 0.05 D) 0.2 E) 0.5 F) 0.8 G) 1.0 Сони back to
Phenotype to Population 1. Describe how the phenotype of individuals with sickle-cell disease influences how common the Hbs allele is in the population: Do individuals with sickle cell disease typically have many offspring? What effect does the fact that individuals with sickle-cell disease do not produce many offspring have on the frequency of the Hbs allele in the population over time? Given this, do you expect the Hbs allele to be common or rare in populations?
Part I. A. Examine the gene pool of this population (Column A) and then choose the answer for the following questions from the box in Column B. show computation (3pts each) 10% 30% 40% 50% 60% 70% 1. What is the frequency of the AA genotype in this population? 2. What is the frequency of Aa genotype in this population? 3. What is the frequency of the aa genoty pe in this population? 4. What is the frequency of the A allele in this population? 5. What is the frequency of the a allele in this population?
Imagine a locus with two alleles. Mutation at this locus changes one allele to the other (i.e. it does not create a new allele). If the rate of mutation from allele 1 to allele 2 is 0.00005 and the rate of mutation from allele 2 to allele 1 is 0.01, what is the equilibrium frequency of allele 2 (Give your answer to 5 decimal places)?
900 bacteria had two recessive alleles out of a total of every 10,000 bacteria. Using the Hardy-Weinberg equation(s), determine the frequency of the recessive and dominant alleles.
The prevalence (frequency) of sickle-cell disease in Canada is quite low, affecting 1/3800 individuals. However, in some African populations 1/25 individuals are affected by sickle-cell disease. The difference in frequency of this allele within the differing populations has to do with the adaptation pressures that exist in the different environments. Individuals with the heterozygous genotype have a survival advantage in environments where the disease malaria is prevalent as the presence of this mutant allele leads to resistance to malaria. Therefore, the sickle-cell disease tends to be more frequent in environments where the malaria parasite is most common. Question: Explain why the sickle-cell disease remains frequent in some populations while it exists in very low frequency in other populations.
r-Weinberg Equilibrium Problem Albinism is a rare genetically inherited trait that is only expressed in the phenotype of homozygous recessive individuals (aa) The most characteristic symptom is a marked deficiency in the skin and hair pigment melanin. This condition can occur among any human group as well as among other animal species. The average human frequency of albinism in North America is only about 5 in 100,00. What are the allelic frequencies of a and A in the North American population if this population is in Hardy-Weinberg equilibrium? What are the frequencies of each of the three possible genotypes in the North American population if this population is in Hardy-Weinberg equilibrium?
1 (b). Nowadays, newborn babies are required to be tested for phynylketonuria (PKU), an autosomal recessive genetic disorder. If untreated, individual homozygous for PKU suffer mental retardation. In a recent year, 4 PKU babies were detected out of 126,o00 tested. Assuming Hardy-Weinberg conditions, What is the percentage of heterozygous carriers? (Give your answer in whole number, no decimal places, and include the % symbol without a space).
Cystic fibrosis (CF) recessive disorder in the Dutch population affects 1 in 1000 people. Calculate the heterozygote advantage for the cystic fibrosis gene (CFTR) in this population. Help: Square root of 0.001 is approximately equal to 0.03.
8% of XY individuals are color blind in a population. Assume Hardy-Weinberg conditions. Submit your answer as it is. a) What is the percentage of color-blind XX individuals? b) What is the percentage of XX individuals who are carriers? c) If this population has 1000 individuals with 50% of male and 50% of female, how many carriers are present in this population? Submit your answer as it is. Do not round up.
In a certain population in the US, the frequency of CCR5-Δ32 homozygous individuals is 1%. Assuming genetic equilibrium, what is the frequency of heterozygotes in this population?

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