One critical function of chondroitin sulfate is to act as a lubricant in skeletal joints by creating a gel-like medium that is resilient to friction and shock. This function seems to be related to a distinctive property of chondroitin sulfate: the volume occupied by the molecule is much greater in solution than in the dehydrated solid. Why is the volume so much larger in solution?

One critical function of chondroitin sulfate is to act as a lubricant in skeletal joints by creating a gel-like medium that is resilient to friction and shock. This function seems to be related to a distinctive property of chondroitin sulfate: the volume occupied by the molecule is much greater in solution than in the dehydrated solid. Why is the volume so much larger in solution?

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter9: Parenteral Medication Labels And Dosage Calculation

Section: Chapter Questions

Problem 4.1P

See similar textbooks

Similar questions

Stearic acid is insoluble in water, and sodium stearate (a soap) is soluble. What causes the difference in solubility? Explain.
Organic polymers have a similar composition to that of common carbohydrates(predominantly composed of Carbon, Hydrogen and Oxygen atoms). By principle, somecarbohydrates readily react with oxygen gas to produce carbon dioxide and water vapor,explain why this principle doesn’t spontaneously work on organic polymer wastes such asPolyethylene terepththalate (PET) and Polystyrene (PS)?
Organic polymers have a similar composition to that of common carbohydrates (predominantly composed of Carbon, Hydrogen and Oxygen atoms). By principle, some carbohydrates readily react with oxygen gas to produce carbon dioxide and water vapor, explain why this principle doesn’t spontaneously work on organic polymer wastes such as Polyethylene terephthalate (PET) and Polystyrene (PS)?
Mixtures of amino acids can be analyzed by first separating the mixture into its components through ion‑exchange chromatography. Amino acids placed on a cation‑exchange resin containing sulfonate (−SO−3)(−SO3−) groups flow down the column at different rates because of two factors that influence their movement: (1) ionic attraction between the sulfonate residues on the column and positively charged functional groups on the amino acids, and (2) aggregation of nonpolar amino acid side chains with the hydrophobic backbone of the polystyrene resin. Note that the ionic attraction is more important than hydrophobicity for this column media. For each pair of amino acids, identify which will be eluted first from a cation‑exchange column using a pH 7.0pH 7.0 buffer.
For each of the following pairs of amino acids, identify the strongest type of intermolecular forces involved when the side chains interact. Explain in terms of the chemical structures of the amino acid side chains. Use the following list: disulfide bridge, hydrogen bonding, hydrophobic interaction, or salt bridge. a) D and H b) C and C c) L and A d) G and S e) N and T
Mixtures of amino acids can be analyzed by first separating the mixture into its components through ionexchange chromatography. Amino acids placed on a cation-exchange resin containing sulfonate ( -SO3-) groups flow down the column at different rates because of two factors that influence their movement: (1) ionic attraction between the sulfonate residues on the column and positively charged functional groups on the amino acids, and (2) aggregation of nonpolar amino acid side chains with the hydrophobic backbone of the polystyrene resin. For each pair of amino acids listed, determine which will be eluted first from the cation-exchange column by a pH 7.0 buffer. (a) Aspartate and lysine (b) Arginine and methionine(c) Glutamate and valine (d) Glycine and leucine (e) Serine and alanine
Dextran is a polymeric carbohydrate produced by certain bacteria. It is used as a blood plasma substitute. An aqueous solution contains 0.582 g of dextran in 106 mL of solution at 21°C. It has an osmotic pressure of 1.47 mmHg. What is the average molecular mass of the dextran?
b) The likelihood of both triglycerides and phospholipids to behave as liquids at a given temperature is affected by their degree of saturation. Explain what saturation is and provide a biochemical explanation for why it affects the likelihood of a lipid to behave as a liquid at a given temperature. 5) a) Proteins have multiple "levels" of structural complexity. Match the type of chemical bond on the left with the level of protein structure that they are specifically involved in maintaining on the right. (Note that more than one letter may apply to each structural level and that each letter may be used more than once or not at all). a. disulphide bonds Tertiary structure b. hydrogen bonds Primary structure c. ionic bonds Quaternary structure d. peptide bonds Secondary structure
Which of these compounds is most soluble in water at pH 7.0? (Note that the non- ionized forms are shown, and remember that ionization will impact solubility!) ( CH3-CH2-CH2-CH2-NH2 CH3-CH₂-CH₂-CH₂-CH3 O CH3-CH2-CH2-CH2-CHO OCH3-CH₂-HCO-O-CH3 (an ester)
For each of the following chemicals, name the general class they belong to, discuss their solubility in water and explain why they are/are not soluble in water (note the numbers are all subscripts): a) CH3(CH2)26COOH b) KCl c) CH3OH
You have been observing an insect that defends itself from enemies by secreting a caustic liquid. Analysis of the liquid shows it to have a total concentration of formate plus formic acid (K₁ = 1.8 x 10-4) of 1.45 M. Further analysis reveals that the concentration of formate ion is 0.015 M. What is the pH of the secretion? pH =
When a small amount of the detergentsodium dodecyl su lfate is dissolved in water, the detergent ions enter the solution as monomeric species. As more detergent is added, a concentration is reached (the critical micelle concentration) at which the monomers associate to form micelles. The critical micelle concentration of SDS is 8.2 mM. The micelles have an average particle weight (the sum of the molecular weights of the constituent monomers) of 18,000. Calculate the number of detergent molecules in the average micelle.