Oral N-acetylcysteine (NAC) exerts a beneficial action in chronic bronchitis by reducing the number of exacerbations. Bontognali et al. [1] conducted a randomized, double-blind study to measure the effectiveness of NAC in the long-term treatment of patients with chronic bronchitis and mild airway obstruction. The response is the number of acute exacerbations per month. The mean value and standard deviation for both experimental and placebo group are given below: Sample size Placebo Mean Sample size 59 Standard Deviation 0.15 Standard Deviation 0.19 70 0.16 To test if there is a statistically significant differences between NAC and placebo in number of observed exacerbations, the author plans to conduct a hypothesis testing at 10% level of significance. Answer the following questions according to the study: NAC Mean 0.11

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NAC Sample size: 59  Mean 0.11 Standard Deviation 0.15

Placebo: Sample size 70 Mean 0.16 Standard Deviation 0.19 

Determine if pooled or non pooled test will be used if we find that the test stastistic F=1.60 with a critical value of 1.72. State standard error of test based on decision upon showing your work. 

 

 

Oral N-acetylcysteine (NAC) exerts a beneficial action in chronic bronchitis by reducing the number of exacerbations.
Bontognali et al. [1] conducted a randomized, double-blind study to measure the effectiveness of NAC in the long-term
treatment of patients with chronic bronchitis and mild airway obstruction. The response is the number of acute
exacerbations per month. The mean value and standard deviation for both experimental and placebo group are given
below:
Placebo
Sample size
59
Mean
Standard Deviation
0.15
Sample size
Standard Deviation
0.19
70
0.16
To test if there is a statistically significant differences between NAC and placebo in number of observed exacerbations,
the author plans to conduct a hypothesis testing at 10% level of significance. Answer the following questions according
to the study:
NAC
Mean
0.11
Transcribed Image Text:Oral N-acetylcysteine (NAC) exerts a beneficial action in chronic bronchitis by reducing the number of exacerbations. Bontognali et al. [1] conducted a randomized, double-blind study to measure the effectiveness of NAC in the long-term treatment of patients with chronic bronchitis and mild airway obstruction. The response is the number of acute exacerbations per month. The mean value and standard deviation for both experimental and placebo group are given below: Placebo Sample size 59 Mean Standard Deviation 0.15 Sample size Standard Deviation 0.19 70 0.16 To test if there is a statistically significant differences between NAC and placebo in number of observed exacerbations, the author plans to conduct a hypothesis testing at 10% level of significance. Answer the following questions according to the study: NAC Mean 0.11
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