Organocuprates predominantly react to give 1,4-addition products with ounsaturated carbonyl species, while Grignard reagents often add to the carbonyl, in a crocess referred to as 1,2 addition. To increase the yield of 1,4-addition products, Cut is added to convert an easily prepared Grignard reagent into an organocuprate reagent in situ. MoBr Cul. THF. -30°C For this reaction draw the structure of the 1,2-addition product prepared without Cul, including stereochemistry, assuming that the major product is derived from the more stable chair contormation. Use the wedge/hash bond toon to indicate stereochemistry where it existi

Organocuprates predominantly react to give 1,4-addition products with ounsaturated carbonyl species, while Grignard reagents often add to the carbonyl, in a crocess referred to as 1,2 addition. To increase the yield of 1,4-addition products, Cut is added to convert an easily prepared Grignard reagent into an organocuprate reagent in situ. MoBr Cul. THF. -30°C For this reaction draw the structure of the 1,2-addition product prepared without Cul, including stereochemistry, assuming that the major product is derived from the more stable chair contormation. Use the wedge/hash bond toon to indicate stereochemistry where it existi

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter14: Elimination

Section: Chapter Questions

Problem 18E

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