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- Based on the five major classes of antibodies given below, which of the following is present on the membrane of naive B cells? Select all that may apply. O IgD O IgA O IgM O IgG O IgEWeigh the following observation: High titers of antibodies for EBVare found in a leukemia patient; a chronically tired, ill businessman; a healthy military recruit; and an AIDS patient. Comment on theprobable significance of antibodies to EBV in human serum.Match the following term with its description or definition. Immunoglobulin domain Amino acids that are separated in the protein chain but come together in the folded protein Antigen that carries several epitopes of the same or different specificity Heavy chain classes Soluble proteins that carry only one copy of the epitope ✓ Choose... IgG, IgM, IgD, IgA, IgE Multivalent antigen Discontinuous epitope Monovalent antigen Repeated barrel-shaped structure Choose...
- Explain the "antigen recognition by cells of adaptive immunity" in a simple way. Thank you, I will use this for infographics. NOTE: BULLET FORMWhat is "defined as the structural differences (diversity) observed in the variable domains of antibodies? This is for immunology.Explain why IgM has a stronger power of agglutination than antibodies of any other class.
- For each blood type in the table below, fill in the expected agglutination result from mixing the blood with eachof the antibodies.Match the antibody classes with their characteristics: IgM IgG IgA IgE IgD Most efficient for agglutination Most abundant in blood; easily penetrates tissue spaces Most abundant in mucus; traps pathogens in mucus Located on the surface of B cells; trace amounts can be found in serum Least abundant; helps stimulate inflammatory responseMatch the antibody isotype with its functional characteristics. Highly effective at activating complement, too large to get to infected tissues Crosses cells, including the placenta, neutralizes toxins Dimeric form crosses the intestinal epithelia using PlgR Crosslinking on the surface of the mast cell leads to degranulation and release of histamine Although the exact function of this isotype is unknown, we know it does NOT fix complement ✓Choose... IgD IgM IgG IgA IgE Choose...
- Complement activation is a cascade reaction, with each component sequentiallyacting on others, in a similar way to the blood-clotting system. Discuss the effectsthat occur when peptides are generated from the activation by either the classicalor the alternative pathway. This is an immunology questionTABLE 6 | Correlation between immune markers and age. Marker NCI PAN LCI LP NK activity (lysis %) R Spearman -0.406 -0.305 -0.239 -0.204 -0.016 Р 0.004 0.035 0.101 0.165 0.913 NCI, Neutrophil Chemotaxis Index; PAN, phagocytic activity of neutrophils; LCI, Lymphocyte Chemotaxis Index; LP, lymphocyte proliferation; NK, natural killer. p is the associated value to the corresponding statistical test.A ‘B’ lymphocyte demonstrates ‘B cell receptors’ on its surface. These receptors have ‘variable’ regions which match the variable regions of the antibodies released by the plasma cell (formed by the activated B lymphocyte). Which of the following types of antibodies forms these ‘B cell receptors’ ? IgG IgA IgD IgE