ssuming a membrane po toplasm ([Ca²+ ]m/[C kpress your answer us

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter23: Enzymes
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Review T Constants
Calcium is an important regulator of the citric acid cycle. Calcium
is transported across the mitochondrial inner membrane by a
Ca+ uniporter that is driven by the negative potential inside the
Part A
matrix.
Assuming a membrane potential across the inner membrane of 184 mV (inside negative), calculate the ratio of the [Ca2+] in the matrix to that in the
cytoplasm ([Ca?+]m/[Ca?+]e) that would exist at equilibrium (i.e., AG = 0).
Express your answer using two significant figures.
[Ca"Im
= 1.7• 106
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Part B
Cytoplasmic [Ca2+] is on the order of 10-7 M in a healthy cell. Based on your answer in Part A, calculate the [Ca?+1 that would exist in the matrix at
equilibrium.
Express your answer to two significant figures and include the appropriate units.
HÁ
?
|1.7 • 10-1
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Transcribed Image Text:Review T Constants Calcium is an important regulator of the citric acid cycle. Calcium is transported across the mitochondrial inner membrane by a Ca+ uniporter that is driven by the negative potential inside the Part A matrix. Assuming a membrane potential across the inner membrane of 184 mV (inside negative), calculate the ratio of the [Ca2+] in the matrix to that in the cytoplasm ([Ca?+]m/[Ca?+]e) that would exist at equilibrium (i.e., AG = 0). Express your answer using two significant figures. [Ca"Im = 1.7• 106 Submit Previous Answers Request Answer X Incorrect; Try Again; 5 attempts remaining Part B Cytoplasmic [Ca2+] is on the order of 10-7 M in a healthy cell. Based on your answer in Part A, calculate the [Ca?+1 that would exist in the matrix at equilibrium. Express your answer to two significant figures and include the appropriate units. HÁ ? |1.7 • 10-1 Submit Previous Answers Request Answer X Incorrect; Try Again; 5 attempts remaining
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