The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown.COOHH₂N-CH|CH ₂pH =CHlonizable -COOHgroupCOO-H₂N-CH1.8pk₁CH2H-COO-CH-HisH+COO-H₂N-CH16.0pk2CH ₂HH N-HisCH-NHCOO-H₂N-CH19.2pk₂CH2-NH₂H-NCHA biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What isthe pH of the resulting solution?

Molarity of Histidine solution = 0.11 MThe volume of Histidine solution taken = 80 mLpH of Histidine…

The amino acid histidine has ionizable groups with pKą values of 1.8, 6.0, and 9.2, as shown. COO COOH H₂N-CH H₂N-CH CH2 H H -N -N MEDE 6.0 CH pk, H N H₂N-CH CH, H -N CH lonizable -COOH group 1.8 pk, COO COO -HisH+ -His CH H₂N-CH 9.2 COO™ pK₂ CH₂ H -N H N -NH →-NH₂ CH A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?

The amino acid histidine has ionizable groups with pKą values of 1.8, 6.0, and 9.2, as shown. COO COOH H₂N-CH H₂N-CH CH2 H H -N -N MEDE 6.0 CH pk, H N H₂N-CH CH, H -N CH lonizable -COOH group 1.8 pk, COO COO -HisH+ -His CH H₂N-CH 9.2 COO™ pK₂ CH₂ H -N H N -NH →-NH₂ CH A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter23: Enzymes

Section: Chapter Questions

Problem 23.65P

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The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COOH H₂N-CH CH₂ H 2 -N H lonizable group 6.0 1.9 7.94 0.11 N H CH -COOH H₂N-CH | CH₂ H 2 N 1.8 COO- I pk₁ C H COO- CH -HisH+ H₂N-CH 6.0 COO- pk ₂. CH₂ H 2 H -His N CH COO™ H₂N-CH 9.2 pk 3 CH₂ H -N с H —NH — —NH, A biochemist makes up 95 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCI. What is the pH of the resulting solution? N CH
The amino acid histidine has ionizable groups with pKą values of 1.8, 6.0, and 9.2, as shown. COOH T H₂N-CH | CH₂ H -O pH UT = ZI Ionizable -COOH group CH H₂N-CH T 1.8 COO- pk₁ CH2 UI COO™ H IZ CH -HisH+ COO™ + H₂N-CH 6.0 pK₂ CH ₂ UI -His H CH -NH COO™ H₂N-CH 9.2 pk3 CH ₂ UI —NH₂ H A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution? CH
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