The reaction of trichloroethanal with water is a nucleophilic addition reaction. It can becatalysed by small amounts of hydroxide ions, OH-.Complete the diagram below to suggest a mechanism for this reaction. Show all the relevantdipoles and curly arrows.ClCIC CCITOOHHCIOCICI-C-C-HHOHThe recommended adult dose of chloral hydrate as a sedative is 250 mg, three times a day.Calculate the mass of trichloroethanal you would need to react with water to make oneweek's supply of chloral hydrate for an adult, assuming a 60% yield.M₁: chloral hydrate, 165.5; trichloroethanal, 147.5

a.) To draw the mechanism, we would first show attack of OH- then reaction of water. To give the…

The reaction of trichloroethanal with water is a nucleophilic addition reaction. It can be catalysed by small amounts of hydroxide ions, OH-. Complete the diagram below to suggest a mechanism for this reaction. Show all the relevant dipoles and curly arrows. Cl CL C C Cl O H H С1 O CI-C-C-H CI H O H The recommended adult dose of chloral hydrate as a sedative is 250 mg, three times a day. Calculate the mass of trichloroethanal you would need to react with water to make one week's supply of chloral hydrate for an adult, assuming a 60% yield. M₁: chloral hydrate, 165.5; trichloroethanal, 147.5

The reaction of trichloroethanal with water is a nucleophilic addition reaction. It can be catalysed by small amounts of hydroxide ions, OH-. Complete the diagram below to suggest a mechanism for this reaction. Show all the relevant dipoles and curly arrows. Cl CL C C Cl O H H С1 O CI-C-C-H CI H O H The recommended adult dose of chloral hydrate as a sedative is 250 mg, three times a day. Calculate the mass of trichloroethanal you would need to react with water to make one week's supply of chloral hydrate for an adult, assuming a 60% yield. M₁: chloral hydrate, 165.5; trichloroethanal, 147.5

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions

Section19.SE: Something Extra

Problem 28VC

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