This is the 8 step synthesis of Ibuprofen. Please check if correct while keeping only 8 steps NH20HN-OHAldoximeCondensation with hydroxylamine-0HAczO, E>CENDenydrationfriedel craft AcylationDE+IsobutyibenzeneduazuaqıhNa OEtclemmenson Reductio.H.+30.2 =HONE?H30°I buprofenAcid Catalyzed hydrdysis

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This is the 8 step synthesis of Ibuprofen. Please check if correct while keeping only 8 steps

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter23: Carbonyl Condensation Reactions

Section23.SE: Something Extra

Problem 71AP

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Question

This is the 8 step synthesis of Ibuprofen. Please check if correct while keeping only 8 steps

NH20H
N-OH
Aldoxime
Condensation with hydroxylamine
-0H
AczO, E>
CEN
Denydration
friedel craft Acylation
DE+
Isobutyibenzene
duazuaqıh
Na OEt
clemmenson Reductio.
H.
+30.
2 =
HO
NE?
H30°
I buprofen
Acid Catalyzed hydrdysis

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