Treating trimethylamine with 2-chloroethyl acetate gives acetylcholine as its chloride. Acetylcholine is a neurotransmitter. Me;N + CH,COCH,CH,CI C,H1,CINO, Acetylcholine chloride Propose a structural formula for this quaternary ammonium salt and a mechanism for its formation.
Q: a) Reaction of 2-methyl propene with methanol in acid-catalyzed medium step by step showing the…
A: Acid catalyzed addition of methanol to 2-methyl propene results in the formation of an ether.In this…
Q: Show how to prepare the following aromatic amines by aromatic nitration, followed by reduction. You…
A: The following c) m-bromoaniline (d) m-aminobenzoic acid can be prepared by aromatic nitration,…
Q: Reduction of ethyl nitrile using H2/Ni produces a.1-propanamine b.propanamine c.ethanamine…
A: Q.1 reduction of ethylnitrile (CH3CN) using H2/Ni gives Q.2 Reduction of nitrobenzene and it's…
Q: E. Cis-2-pentene Preamble: A student chemist in an attempt to synthesise compound B from the…
A: The given reaction from p-chlorobenzaldehyde with ammonia is a condensation reaction where water…
Q: Propose a mechanism for formation of 2-carbethoxy-4-butanolactone and 4-butanolactone…
A: 2-carbethoxy-4-butanolactone
Q: A solution of acetone [(CH3)2C=O] in ethanol (CH3CH2OH) in the presence of a trace of acid was…
A: Ketones react with alcohol in the presence of acid H+ to form acetal. Acetal contains two alkoxy…
Q: Which of the following compounds would be used to prepare an enamine from 3-pentanone? A.…
A: GivenReactant 1 = 3-pentanoneReactant 2 = To be determined Product An enamine
Q: A solution of acetone [(CH3)2C = O] in ethanol (CH3CH2OH) in the presence of a trace of acid was…
A: IR spectroscopy study the interaction of infrared radiation with matter. Its range for analysis of…
Q: (a) Show how you prepare the following esters from the corresponding acids and alcohols using…
A:
Q: O₂N -NO₂ H₂O NH₂ NH₂ 2 O-N+
A:
Q: Phenacetin is an analgesic compound having molecular formula C10H13NO2. Once a common component in…
A: From the IR spectrum a) It is observed that a peak around 1600 cm-1 shows that an amide group is…
Q: 10) Which of the following will be the major product in the following reaction sequence? NO2 EN C 1)…
A: Primary amine - RNH2 , -NH2 group has only one carbon atom Secondary amine - R2NH, two carbon atom…
Q: Show how to synthesize the following amines from the indicated starting materials…
A: Given The given organic compounds are N-butylpiperidine and piperidine.
Q: Propose a mechanism for this reaction
A:
Q: Imines can undergo reduction reactions with sodium borohydride to produce amines by a similar…
A:
Q: What generalization trends may be extracted from the following series in terms of solubility with…
A: Acid base reaction is faster than other reaction so Base will react first with an acid. Now in set…
Q: H,N NH COC,H; C. C,H5. 1. C,H,O¯N * 2. H,0 9. 2) \4. C=0 O + 2C,H;OH C,H, NH C,H; COC,H, H,N…
A:
Q: Following is a retrosynthetic analysis for the anthelmintic (against worms) diethylcarbamazine. N.…
A: Diethylcarbamazine is an organic compound used to treat Filariasis. It is formed y treating…
Q: B1) Suggest a brief retrosynthetic analysis for 4-7 until you arrive at the starting material shown…
A: Since you have asked multiple questions, we will answer the first one for you. To get the remaining…
Q: 5. The acyl group is a protecting group for amines which can be deprotected by treatment with sodium…
A:
Q: The two most general amine syntheses are the reductive amination of carbonyl compounds and the…
A: Amines are the compounds that have NH2 group present in it. The lone pair of nitrogen can be donated…
Q: 1. Write the structure of the aminal or hemiaminal intermediate and the imine product formed in the…
A: “Hey, since there are multiple questions posted, we will answer first question. If you want any…
Q: Predict the products formed when cyclohexanone reacts with the following reagents. h) sodium…
A: SOLUTION: Step 1: The reaction of sodium acetylide with the cyclohexanone (ketone) is an example of…
Q: Spasmolytol, as its name suggests, is an antispasmodic. Given this retrosynthetic analysis, propose…
A: Spasmolytol is an antispasmodic drug that used to relieve the pain of involuntary muscle. Salicylic…
Q: Treating a Grignard reagent with carbon dioxide followed by aqueous HCI gives a car- boxylic acid.…
A:
Q: Show how to synthesize the following amines from the indicated starting materials below. Each of the…
A: The question is based on the concept of chemical reactions. we have to convert benzene to meta-bromo…
Q: The synthesis of the following compound involves the use of an epoxide. Describe the retrosynthetic…
A: Under acidic condition ring opening of epoxide occurs from the more hindered site.
Q: Moxisylyte, an a-adrenergic blocker, is used as a peripheral vasodilator. Propose a syn- thesis for…
A: m- Cresol reacts with propene in the presence of phosphoric acid gives thymol, thymol undergoes…
Q: Give the shortest route to produce the desired products 1. cyclobutanoic acid to ethyl-cyclobutyl…
A: 1. Cyclobutanoic acid on treatment with SOCl2/pyridine give corresponding acid chloride which on…
Q: „CHO NH3 H2. Ni A -H20 60 °C, 90 atm CI
A: Since the N in NH3 is having lone pair electron and C attached to O in the benzene reactant is…
Q: The reaction of cyclohexanone (1) and N,N-dimethylamine (2) with (i) sodium triacetoxyborohydride…
A: This is an example of reductive amination reaction in which an aldehyde or ketone reacts with amine…
Q: (f) Ethanoyl chloride (CH, COCI) reacts with benzene. According to the equation below to give phenyl…
A: (iv) The reaction of benzene with ethanoyl chloride to give phenyl ethanoate is given as:C6H6…
Q: Write the mechanisms of those two reactions with explanation
A: The mechanism can be given as follows:- Quaternization reaction: In the given compound lone of N…
Q: Show how diazonium salts could be used to synthesiz a. p-chlorobenzoic acid from p-chloroaniline b.…
A: Hello. Since your question has multiple sub-parts, we will solve the first three sub-parts for you.…
Q: The condensation of pyrrolidine with acetaldehyde gives an enamine product. Select the best answer…
A:
Q: The following scheme shows the retrosynthetic analysis of 1-isopentylaziridine to form series of…
A:
Q: Treatment of r-butyrolactone with two equivalents of methylmagnesium bromide, followed by hydrolysis…
A:
Q: 3 Treatment of 1-aminoadamantane, C„H„N, with methyl 2,4-dibromobutanoate in the presence of a…
A: In the given SN2 reaction, 1-aminoadamantane act as a nucleophile and it make a bond with terminal…
Q: Propose a synthesis for diphenhydramine starting from benzophenone, benzoic acid, and 2-(N,…
A: Synthetic method for diphenhydramine: Benzophenone undergoes reduction using sodium borohydride on…
Q: Treatment of benzene with succinic anhydride in the presence of polyphosphoric acid gives the…
A:
Q: CH3CH2CN reacts with CH3CH2MgBr followed by acidic hydrolysis produces a(n) O 2 Penatanone O Butane…
A:
Q: 1. LIAIH, 2. H2O
A: LiAlH4 is a reducing agent which converts C=O group to CH2 group.
Q: Predict the products of the following reactions.(a) phenol + acetic anhydride (b) phenol + acetic…
A: (a) Acetic anhydride is a symmetric molecule. Both carbonyl carbons are attached to methyl group.…
Q: Preamble: A student chemist in an attempt to synthesise compound B from the aromatic aldehyde. Use…
A: Aldehyde and ketone reacts with ammonia gas because there is a partial +ve charge on carbon making…
Q: Propose a synthesis, showing reagents and conditions, to make 4-bromoaniline starting from benzene.…
A: First we need to convert the bromine into aniline to produce 4-bromoaniline finally. Hence to do…
Q: 二 ニ。 二 二人 HO, んこんー ん HO.
A: N. Amide to amine using LiAlH4. O. Acid chloride reaction with amine (Acyl substitution). P. Acid is…
Q: Give the expected products of lithium aluminum hydride reduction of the followingcompounds (followed…
A: ANSWER: Step 1: (a). Butyronitrile on reducing with lithium aluminum hydride followed by hydrolysis…
Q: Following is a retrosynthetic analysis for the synthesis of the herbicide (S)-Metolachlor from…
A: The retrosynthetic method is used to predict the starting material from product structure by…
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 2 images
- Following are structural formulas for amphetamine and methamphetamine. H NH, CH3 (a) (b) Amphetamine (racemic) Methamphetamine (racemic) The major central nervous system effects of amphetamine and amphetamine-like drugs are locomotor stimulation, euphoria and excitement, stereotyped behavior, and anorexia. Show how each drug can be synthesized by reductive amination of an ap- propriate aldehyde or ketone and amine.14. What is the IUPAC name for the following compound? NH- (a) propyl propanamide (b) propyl propanoate (c) N-propylptopanamine. (d) N, N-propylpropanamide (e) N-propxlpropanamidenoradrenaline and serotonin in the spinal cord. Deduce the structure of this new compound, given its molecular neuron to another. Noradrenaline (also called norepinephrine) and serotonin are neurotransmitters that act in its) Neurotransmitters are small molecules that are produced by the body to send messages from one the central nervous system. A recently report synthetic compound has effects that are similar to baul formula (CəH13NO) and the following 'H NMR spectral data. Show your work by labeling your proposed structure with the corresponding letters for the signals listed below. a) 1.1 6 (2H, broad singlet) b) 2.7 6 (2H, triplet) c) 2.9 6 (2H, triplet) d) 3.8 6 (3H, singlet) e) 6.8 6 (2H, doublet) f) 7.1 6 (2H, doublet)
- Paroxetine (Paxil) is an antidepressant that is a member of a family of drugs known as Selective Serotonin Reuptake Inhibitors (SSRIS). This family of drugs also includes fluoxetine (Prozac) and sertraline (Zoloft). SSRIS work by inhibiting the reuptake of the neurotransmitter serotonin in the synapses of the central nervous system follow- ing release of serotonin during excitation of individual nerve cells. Between firings, the serotonin is taken back up by a nerve cell in preparation for firing again. Inhibition of reuptake has the effect of increasing the time serotonin molecules remain in the syn- apses following excitation, leading to a therapeutic effect. In one synthesis of parox- etine, the following reagents are used. Draw the structures of synthetic intermediates A and B. F НО SOCI, A B HO PyridineAnswer the following questions based on the information provided. (a) Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension. One of the key step of Sildenafil synthesis is shown below. OEt O OEt O i) Amine HO CHO ii) H20 washing to remove the HCI residue CI N. i) What's the structure of Amine reagent? Amine structure ii) Why does not carboxyl acid react with amine? iii) Draw the mechanism of the reaction.What are the derivate reagents for the following compound: MDMA (N-methyl-N-trifluoroacetyl-3,4-methylenedioxyamphetamine)?
- In the mid-1930s a substance was isolated from a fungus that is a parasite of ryes and other grasses. This alkaloid, lysergic acid, has been of great interest to chemists because of its strange, dramatic action on the human mind. Many derivatives of lysergic acid are known, some with medicinal applications. Perhaps the best known derivative of lysergic acid is the potent hallucinogen lysergic acid diethylamide (LSD): మగవా జి N-H LSD (CH25N;O) Like other alkaloids, LSD is a weak base, with Kp = 7.6 × 107. What is the pH of a 0.94 M solution of LSD? pH =The name of following amine H3C-CH3 compound is N-methylbenzeneamine, and it is a tertiary aliphatic N,N-Dimethylaniline, and it is a tertiary aliphatic N,N-Dimethylaniline, and it is a tertiary aromatic N-methyl-N-methylaniline, and it is a tertiary aliphatic N-methyl-N-methylaniline, and it is a tertiary aromaticBisphenol A is widely used as a building block in polymer synthesis and is found in the polycarbonate hard plastics of reusable drink containers, DVDs, cell phones, and other consumer goods. Bisphenol A is reported to have estrogenic activity, and its widespread occurrence in our environment is a potential concern. Describe one or two biochemical experiments that could be done to compare the activity of bisphenol A with that of its estradiol, its structural relative.
- Define the Mechanism - Conversion of Carboxylic Acids to Amides with DCCIn an attempt to synthesize compound C through a two-step process, a chemist discovered after completing the first step that they had inadvertently produced two distinct compounds, A and B. Upon examining the infrared spectroscopy (IR) results, it was observed that both A and B exhibited peaks indicative of a ketone and an ester group. Please provide the molecular structures of A and B. OEt NaOEt ΕΙΟ A B In a chemical experiment, they noticed that both components, A and B, from a combined sample turned into a new compound, C, during the following stage. The task is to determine what compound C looks like and explain how compound A or B changes into compound C through a reaction. Compound C should be the primary molecule containing carbon created in this process, not just a by-product. A B H3O+, H₂O, A Mechanism = сThe two most general amine syntheses are the reductive amination of carbonyl compounds and the reduction of amides.Show how these techniques can be used to accomplish the following syntheses.(a) benzoic acid S benzylamine (b) benzaldehyde S benzylamine(c) pyrrolidine S N@ethylpyrrolidine (d) cyclohexanone S N@cyclohexylpyrrolidine(e) HOOC¬(CH2)3 ¬COOH S pentane@1,5@diamine (cadaverine)