Using the pedigree below for an autosomal dominant disorder to determine the phase (which ones are recombinants and which are non-recombinants? Identify them by pedigree position (11, 112, etc.) (SLO4) 11 III 2/2 2/2 1/2 1/1 2/2 2/2 2/2 2/2 1/2 2/2 1/2 2/2 1/2 2/2 Calculate the LOD score for each theta below for the pedigree above. Note: keep lots of places behind the decimal until the very end for accuracy. (SLO4)

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Using the pedigree below for an autosomal dominant disorder to determine the phase (which ones are
recombinants and which are non-recombinants? Identify them by pedigree position (11, 112, etc.) (SLO4)
1
11
III
2/2
1/2
1/1
-O
2/12
2/2 2/2 2/2 2/2 1/2 2/2 1/2 2/2 1/2 2/2
a. 0.01
b. 0.1
c.
0.2
Calculate the LOD score for each theta below for the pedigree above. Note: keep lots of places behind
the decimal until the very end for accuracy. (SLO4)
Transcribed Image Text:Using the pedigree below for an autosomal dominant disorder to determine the phase (which ones are recombinants and which are non-recombinants? Identify them by pedigree position (11, 112, etc.) (SLO4) 1 11 III 2/2 1/2 1/1 -O 2/12 2/2 2/2 2/2 2/2 1/2 2/2 1/2 2/2 1/2 2/2 a. 0.01 b. 0.1 c. 0.2 Calculate the LOD score for each theta below for the pedigree above. Note: keep lots of places behind the decimal until the very end for accuracy. (SLO4)
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