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What are the advantages of granulation ? during tablet formulation. Define
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- Concentration (mg/L) Time (hours) Sustained-Release Tablet Oral Solution 0.5 2.26 19.80 1 4.57 18.31 1.5 5.27 15.49 2 6.73 12.37 7.36 9.62 4 7.40 6.85 5 7.50 5.52 6.24 3.10 8. 4.70 1.79 12 2.76 1.58Outline in detail the procedure for celloidin embedding .Give one advantage and one disadvantage of pharmaceutical solid dosage forms. Explain each advantage and disadvantage thoroughly.
- Describe drawbacks associated with the use of topical powder dosage forms, and provide examples of other dosage forms that would overcome these drawbacks.Explain Emulsions. What variations are there? Give an illustration of each category. Create two emulsification programmes.Patch clamp What is patch clamp technique? Identify two features of the patch clamp technique that make it a useful tool in studying cellular electrophysiology. Explain each thoroughly. What is the role of the reference electrode in the patch clamp technique? Discuss how it works.
- What types of problem will occurs if excipients are not use during formulation of suspension?Many heavy metals are used in antiseptics. Explain the oligodynamic effect and provide a clinical example of the use of heavy metals.What is the clinical significance of ESR determination? Differentiate Wintrobe from Westergreen regarding accuracy of the test in a tabulated order. NOTE: Kindly asnwer all the questions. Thank you!
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