What is a tumor suppressor? What is an oncogene?
Q: What are Tumor Markers ?
A: Cancer is the abnormal growth and multiplication of normal cells. Cancer cells divide rapidly.…
Q: How can a defect in p53 gene contribute to cancer development?
A: Cancer is an abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some…
Q: Why is infection likely to occur at the tumor site?
A: Unlike cancer, tumor won't spread to different areas. It will be formed as a lump in any part of the…
Q: What is the link between epigenetics and cancer?
A: Epigenetics is considered as the study in which the gene shows its behavior according to the…
Q: Define tumor-suppressor genes. Why is a mutated single copy of a tumor-suppressor gene expected to…
A: The repeated and uncontrollable division of cells forms a large mass called the tumor. Tumors might…
Q: What is apoptosis? How is it beneficial to the body?
A: APOPTOSIS: * Apoptosis is a type of programmed cell death in which some steps in cell will leads to…
Q: What causes cancer?
A: A collection of related diseases is called “cancer”. This occurs due to the uncontrollable growth of…
Q: What is a tumor?
A: All living creatures and body tissues are made up of the smallest unit that can live on its own. The…
Q: Can we cure cancer by restoring the function of tumor suppressor proteins such as mutant p53 or pRb?…
A: Cell division is a process through which a cell produces two identical daughter cells. Cell division…
Q: What are Two kinds of cancer-producing mutations?
A: Cancer is defined as any one of a large number of diseases characterized by the development of…
Q: What is happening in all cancer? What process is this disrupting?
A: Cancer in simple term can be referred to a set of diseases which are caused by the production of an…
Q: What is the properties of stem cells?
A: Cells are the basic building units. They help to form a whole organism. These cells perform…
Q: Define tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene…
A: Tumor-supressor genes: Tumor-suppressor genes is defined as normal genes that will slow down the…
Q: Is cancer a genetic disease ?
A: Cancer includes overgrowth of the cells above the normal number. It is studied under the domain of…
Q: What is the difference between an oncogene and a tumor-suppressorgene? Give two examples of each…
A: Cancer is defined as the biological disorder in which the cells undergo uncontrolled growth and cell…
Q: What are tumors?
A: Cancer involves many diseases in which the living cells evade control mechanisms that generally…
Q: How can a mutation in a tumor-suppressor gene contribute to the development of cancer?
A: Tumor-suppressor genes are like any other normal genes whose functions include slowing down cell…
Q: Explain about the Cancer-causing gene formed by a mutation in a proto-oncogene ?
A: In genetics, the mutation is defined as the changes or alteration in the DNA sequences which result…
Q: What is cancer?
A: In a multicellular creature, cell division is a natural process. Cell division has usually defined…
Q: What is the role of the microenvironment in cancer development and progression?
A: Progression of cancer is the steps of progress of this disease, it includes many stages: Stage I…
Q: What is the working of Tumor suppressor genes ?
A: There are two types of genes that are associated with tumors: Oncogenes: These genes when directly…
Q: What is apoptosis, and under what circumstances do cells undergo this process?
A: A lysosome is a membrane bound organelle that contains (hydrolytic enzymes) digestive enzymes. The…
Q: How do cancers protect themselves from cell death?
A: Introduction :- A multicellular organism's life cycle must include cell death. Most cell deaths…
Q: How do oncogenes differ from tumor suppressor genes?
A: Oncogenes are a physically and functionally diverse set of genes, the protein products of which act…
Q: What would be the effect of a mutation that inactivates the p14ARF tumor suppressor upon p53…
A: p53 is known as a cellular tumor antigen 53 is a protein found in vertebrates that is responsible…
Q: How Mutations Cause Cancer Phenotypes?
A: The medical condition of cancer is generally characterized by the presence of a cluster of cells…
Q: What are Ras protein and p53? How can mutations in the genes for these proteins contribute to…
A: TP53 is the gene that translates the protein called tumor protein p53 which acts as a tumor…
Q: Why does inflammation fuel cancer development/invasion?
A: Introduction :- The immune system uses inflammation as one of its defence mechanisms against…
Q: Define oncogene, proto-oncogene, and tumor-suppressor gene.
A: The most common gene in people with cancer is p53 or TP53. More than 50% of cancers involve the lost…
Q: Which type of mutation would NOT be involved in the inactivation of a tumor suppressor gene?
A: Normal cell growth in body is controlled by - 1. Protooncogene or cellular oncogene - Protooncogene…
Q: What is apoptosis and its major mechanism?
A:
Q: What is the relationship between the cell cycle and cancer production?
A: A cell is the fundamental, structural, and functional unit of the living cell bounded with a cell…
Q: What is the difference between a proto-oncogene and a tumor suppressor gene? How can mutations in…
A: Proto-oncogenes are normally switched off. But when they get activated they cause tumors. On the…
Q: How tumor-suppressor mutations contribute to cancer?
A: Cancer - Cancer is a type of disease in which cells divide in an uncontrolled manner. The cells…
Q: How does the normal p53 protein inhibit cancer development?
A: Tumor-suppressor genes code for proteins that repair damaged DNA (preventing a cell from turning…
Q: If a mutation occurs in an embryonic stem cell that alters cell proliferation there is potential for…
A: Stem cells are undifferentiated cells that have potential to develop many different types of cells…
Q: How might overexpression of proto-oncogenes lead to abnormal cellular proliferation?
A: A proto-oncogene is a cell's normal gene. Proto-oncogenes are plentiful. Each one is in charge of…
Q: Why are oncogenes usually dominant in their action, whereas tumor-suppressor genes are recessive?
A: BASIC INFORMATION ONCOGENES When there is alteration in the proto-onco genes then it leads to the…
Q: Is PI3K a proto-oncogene or a tumor suppressor gene? Why
A: PI3K means Phospho inositol 3 kinase gene.It is involved in signalling pathways.It is the mutation…
Q: How do we know that malignant tumors arise from a single cell that contains mutations?
A: Malignant tumors are multicellular cell masses invading normal tissues and disrupting their function…
Q: What are the Characteristics of Cancer Cells?
A: Cancer is a disease of cells, in which the controls that normally restrict cell proliferation do not…
Q: What is the role of regulatory gene mutations in cancer?
A: Regulatory genes are defined as genes which control or regulate the expression of one or multiple…
Q: What is programmed cell death or PCD?
A: A programmed cell death (PCD) is a phenomenon by which those damaged cells are removed which have…
Q: What is haploinsufficiency? How might it affect cancer risk?
A: The term in genetics that explains the function of the dominant gene in the representation of…
Q: Which are the Genetic Basis of Cancers?
A: Cancer is a disease related to abnormal growth of cells where the cells have the potential to spread…
Q: Explain the difference between a proto-oncogene and a tumor-suppressor gene.
A: Cancer is the state of uncontrolled cell division.
What is a tumor suppressor? What is an oncogene?
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- how do tumor suppressor genes and proto-oncogenes causes cancer?Which of the following is true of tumor suppressor genes? Group of answer choices a) If this gene is overactive, it becomes an oncogene b) If one of the alleles is mutated, there is usually little effect. Two inactivating mutations are usually required for loss of function (recessive mutation). c) If one copy is lost, the gene no longer functions (dominant mutation) d) Tumor suppressors genes usually cause mitosis or cell growth e) Tumor suppressor genes decrease apoptosisWhat are the normal functions of the BRCA1 tumor suppressor gene?