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What is the most straightforward evidence at the molecular level in support of the idea that modern humans first appeared in Africa?
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- The Out of Africa hypothesis (also called the African Replacement hypothesis) proposes that Homo sapiens arose in Africa and evolved there for several hundred thousand years. Then, some 85,000 years ago, a small band of Homo sapiens migrated out of Africa and populated the remainder of the world. Based on this hypothesis, what predictions would you make about worldwide human variation in mtDNA?A number of comparisons of nucleotide sequences among hominidsand rodents indicate that inbreeding may have occurredmore often in hominid than in rodent ancestry. Bakewell et al.(2007. Proc. Nat. Acad. Sci. [USA] 104: 7489-7494) suggest thatan ancient population bottleneck that left approximately 10,000 humans might have caused early humans to have a greaterchance of genetic disease. Why would a population bottleneckinfluence the frequency of genetic disease?There are two hypotheses to explain the pattern of Human Evolution: 1) Progressive Evolution of a Single Lineage ; 2) Evolutionary Radiation Which of these hypotheses are supported by evidence, and briefly explain why? Please explain in details
- For each of the following, indicate whether it is true or false according to the current understanding of most scientists. Put either an F or a T in each box. A) Humans and chimpanzees shared a common ancestor between 6 and 8 million years ago B) Homo sapiens were already living in Europe when the first Neanderthals arrived. C) Humans gradually evolved from ape-like creatures in a linear fashion with each species in the line slowly evolving into a more modern form. D) Early Homo sapiens interbred extensively with Neanderthals and Denisovans forming a new hybrid species. E) Homo sapiens have been the only hominin species on earth for the last 10,000 years.Which of the following best explains the number of similarities between the amino acid sequences of the Drosophila Hedgehog protein and the Chicken Indian Hedgehog protein? O A. The Drosophila hedgehog gene evolved from hedgehogs, which are distantly related to birds. O B. Both genes evolved from a gene present in the last common ancestor of Drosphila and chickens, and the number of differences reflects the amount of time that has elapsed during the evolution of these two lineages. a During the evolution of Drosophila and chickens, a hedgehog like gene arose independently in each lineage, then the gene that arose in chickens diversified. A These genes are unrelated, and the fact that they are similar is only because the proteins need to have similar biochemical properties. They are unrelated because chickens don't have segments and Drosophila larvae don't have limb buds.Some people think that many of our uniquely human traits arose by sexual selection. Over thousands of years, women attracted to charming, witty men perhaps prompted the development of human intellect beyond what was necessary for mere survival. Men attracted to women with juvenile features may have shifted the species as a whole to be less hairy and softer featured than any of our simian relatives. Can you think of a way to test these hypotheses?
- How, specifically, is the concept of ALLOMETRY relevant to the phylogenetic position of Homo floresiensis? Because if allometry explains the anatomy of Homo floresiensis then we can conclude that it is not separate species but instead a member of our species. Although most mammals on islands go through a process of getting smaller, Homo floresiensis evolved from a smaller ancestor to be bigger, meaning that allometry is an important factor. Mutations in the allometry allele are associated with many of the characteristics of Homo floresiensis. Because Homo floresiensis is so much smaller than other members of the genus Homo, it is important to determine how shape changes associated with smaller size impacted the species. Because Homo floresiensis had both small- and large-bodied forms, variation within the species is in large part dictated by allometry.Crickets have colonized each island in the Hawaiian Archipelago. Geological data indicates that Kauai is the oldest island in the chain and Hawaii is the youngest. Researchers hypothesized that crickets sequentially colonized islands as they rose out of the ocean and created a cladogram based on molecular relationships to test this idea. 1) Mark & label (as “MRCA”) the most recent common ancestor for all crickets on the island of Kauai. 2) Molokai is roughly equally distant from Oahu as Maui, but not equally related. Are Molokai crickets more closely related to those on Oahu or Maui?_________Once nuclear DNA sequencing became fast and able to handle sequencing ancient DNA, living humans were found to have some Neanderthal genes. Is this finding clear evidence that some early modern humans did indeed hybridize with Neanderthals? Why?
- How does the fact that all ethnic groups except Africans contain some Neanderthal DNA (1–4 percent of their DNA) support the out-of-Africa hypothesis for the origin of modern humans (Homo sapiens)?The ancestor of cats was presumably homozygous for wild type at all of the described genes. What was the phenotype of this ancestral cat at each of these loci? 1)Dark grey with black mackerel stripes 2)Light grey female with dark grey mackerel stripes 3)Light brown male with chocolate tips 4)Black female with large white patches 5)Cream male with small white patches and orange mackerel stripes 6)A uniformly colored black catEach of the following three questions contains two lists. The first is a list of some characteristics of our own species, Homo sapiens, that distinguish it from LUCA. The second is a list of possible sequences (reading from left to right) in which these novelties were acquired by our ancestors during the course of human evolution. Choose the number of the correct sequence. If none is correct, choose "None of the above." Here is the first pair of lists: A. Bilateral symmetry B. Bony skeleton C. Mitochondria D. Notochord E. Multicellularity O D, E, B, A, C O C, E, A, D, B O E, C, A, D, B O A, E, C, D, B O None of the above