When BHBA is consumed in the drink HVMN Ketone Ester it eventually passes into the bloodstream. Blood is buffered at a pH of 7.4. Calculate the ratio of conjugate base to conjugate acid for BHBA in the blood stream. Which is the principal chemical form in the bloodstream, the conjugate acid or the conjugate base? C.

Chemistry & Chemical Reactivity
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Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
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Chapter24: Biochemistry
Section: Chapter Questions
Problem 34GQ: The first step of the metabolic process known as glycolysis is the conversion of glucose to glucose-...
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Part c
beta-Hydroxybutyric acid (BHBA) is an interesting molecule that is constantly
blood stream. BHBA becomes elevated when your metabolism is driven into
circulating in
ketosis, a state that occurs when carbohydrates and glycogen are no longer available for metabolism
and your body turns to using fats instead. Some athletes believe that forcing themselves into ketosis
before a competition increases performance and products such as the drink HVMN Ketone Ester
have been developed for this purpose. The structure of BHBA is shown below:
your
OH
HO,
a. Draw the structures of the conjugate acid and conjugate base forms of BHBA.
b. Calculate the pH of a solution that contains 0.0353 mole of BHBA in 500 mL of water given
that the pKa of BHBA is 4.70. Which is the principal chemical form of BHBA in aqueous
solution, the conjugate acid or the conjugate base?
When BHBA is consumed in the drink HVMN Ketone Ester it eventually passes into the
bloodstream. Blood is buffered at a pH of 7.4. Calculate the ratio of conjugate base to
conjugate acid for BHBA in the blood stream. Which is the principal chemical form in the
bloodstream, the conjugate acid or the conjugate base?
C.
Transcribed Image Text:beta-Hydroxybutyric acid (BHBA) is an interesting molecule that is constantly blood stream. BHBA becomes elevated when your metabolism is driven into circulating in ketosis, a state that occurs when carbohydrates and glycogen are no longer available for metabolism and your body turns to using fats instead. Some athletes believe that forcing themselves into ketosis before a competition increases performance and products such as the drink HVMN Ketone Ester have been developed for this purpose. The structure of BHBA is shown below: your OH HO, a. Draw the structures of the conjugate acid and conjugate base forms of BHBA. b. Calculate the pH of a solution that contains 0.0353 mole of BHBA in 500 mL of water given that the pKa of BHBA is 4.70. Which is the principal chemical form of BHBA in aqueous solution, the conjugate acid or the conjugate base? When BHBA is consumed in the drink HVMN Ketone Ester it eventually passes into the bloodstream. Blood is buffered at a pH of 7.4. Calculate the ratio of conjugate base to conjugate acid for BHBA in the blood stream. Which is the principal chemical form in the bloodstream, the conjugate acid or the conjugate base? C.
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