Which of the following changes occur with a double-stranded DNA if it is heated to 95 C at neutral pH?OA Increase in the absorption of uitraviolet light at 260 nmOB. Unwinding of the helical DNA structureOc Separation of the two DNA strandsDo.Hydrolysis of the N-glycosidic bond belween the base and deoxyriboseDE Breakage of the phosphodiester bonds belwean adjacent ucieotidesDr. Breakage of the hydrogen bonds between guanines and cytidines.

The hereditary substance found in practically all species is DNA or deoxyribonucleic acid. DNA aids…

Answered: Which of the following changes occur…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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The two strands for the helix-shaped DNA molecule are heldtogether by electrostatic forces as shown in class. Due to electron sharing, themagnitude of the net average charge on the H and N atoms, each, is 0.2e. Thenet average charge on the C and O atoms, each, is 0.4e. The distance betweenany two adjacent atoms on the same molecule is 0.1nm. Since electric fieldsdecrease as an inverse square law, they die off quickly with distance. So, theonly fields that really contribute to any given bond are due to the 3 atomsalong the red dotted line in the class diagram (two atoms on one'molecule andone atom on the other molecule).Calculate the electric fields and net force between a thymineand an adenine pair.=Calculate the electric fields and net force between a cytosineand a guanine pair.nConsider the OHN bond in the AT nucleotide. Can theelectric field be zero anywhere along the axis of this bond? If not,explain why not. If so, find where the electric field is zero.
Examine the 5'- 3 sequence of bases of the DNA molecules (A D) shown below. I am only showing you the 5 - 3' strand of each molecule, but you can imagine the complementary 3' - 5' strand for each molecule. Which double-stranded molecule is held together by 10 hydrogen bonds? O AAAT O ATAG O TGTC O GCGA
The joining of a new nucleotide to a growing strand during DNA synthesis leads to the formation of a phosphoester bond and involves O a nucleophilic attack of the terminal P atom of the growing strand on the electrophilic 3-0 atom of the growing strand O a nucleophilic attack of the terminal 3'-0 atom of the growing strand on the electrophilic P atom of the incoming nucleotide O an electrophilic attack of the terminal 3'-O atom of the growing strand on the nucleophilic P atom of the incoming nucleotide an electrophilic attack of the terminal Patom of the growing strand on the nucleophilic 3-O atom of the growing strand
Spring O The nucleotides in one strand of DNA are held together by hydrogen bonds. The nitrogenous bases in one strand are held to the nitrogenous bases of the other strand by phosphodiester bonds. ules Purine nucleotides always form base pairs with other purines, and pyrimidine nucleotides always form base pairs with other pyrimidines. nments es O The diameter of a DNA molecule is the same along its entire length due to the specific complementary base pairing of the DNA. ouncements -le Question 5 1 pts millan Higher ation Media In the sequence 5'-TCCGGA-3', an available phosphate group would be found at the 5' end of the nucleotide labeled "T." ia Gallery aborations O True False neCoach Roster cussions No new data to save. Last checked at 5:03pm Submit Quiz 327 FEB CC 3. MacBook Pro
Show the structure of a DNA where the lead strand is ATCG. Show H-, glycosidic, phosphoester bondings.
Which of the following statements about the DNA double helix is FALSE? O The base pairs are located in the center of the helix O The plane of the base pairs is perpendicular to the direction of the deoxyribose- phosphate backbone O The two strands have the same 5' to 3' direction (i.e, are parallel) O The base pairs stack on one another O The deoxyribose-phosphate backbone is on the outside of the helix
Hydrolysis of the N-glycosyl bond between deoxyribose and a purine base in DNA creates an apurinic (AP) site. An AP site is more thermodynamically destabilizing to a DNA molecule than is a mismatched base pair. Examine the structure of an AP site. HN H₂N N 0 Guanine -O-P-O-CH₂O. H₂N H HN H H H Hod H ofo -0- Guanosine residue (in DNA) -0-CH₂ H H H Apurinic residue H OH H
which type of base pairs uf any allow the dna to remain double dtranded at higher temperature? gc at both neither
Match the statement with the phase of the cell cycle it describes. The nucleus divides O G1 G2 O mitosis O cytokinesis
What provides the negative charge associated with DNA? O The phosphate groups O The nitrogenous bases O The deoxyriboses O The sulfhydryl groups O The riboses
What structural aspect of the DNA facilitates dissociation of the two DNA strands for replication? Covalent bonds between sugars and phosphate groups Purine-pyrimidine pairing 3' end phosphorylation O Antiparallel DNA strands O Hydrogen bonding between paired bases
Phosphate T Sugar G G A 4 Bases O CCCACTTGAG GAGTTCACCC GGGTGAACTC CTCAAGTGGG O None of the Above Suppose the DNA molecule shown at left was produced in the test tube from deoxynucleotide 5'-triphosphates. What is the correct primary sequence of this piece of DNA?

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