Why is peptide synthesis carried out from C terminus to N terminus using dicyclohexylcarbodiimide (DCC)? Can you illustrate the explanation with a mechanism/drawing?

Q: Determine the amino acid sequence of a polypeptide from the following data:Acid-catalyzed hydrolysis…

A: Given polypeptide chain has 13 amino acids in its sequence. In the given polypeptide, N-terminal…

Q: What are the basic steps to synthesize a dipeptide using solid phase peptide synthesis assuming…

A: We have to predict the correct  steps for dipeptide synthesis.

Q: What reaction conditions are needed to achieve complete peptide hydrolysis to its amino acid…

A: 1- In this question, first we will discuss about Reaction conditions for peptide Hydrolysis, then we…

Q: ?(acilbase reacin)

A: In the given reactant carbon atom possess a partial negative and lithium atom possess a positive…

Q: Show the mechanism and explain how the Ala-Val-Ile peptide bond is formed.

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Q: Which of the following reagents is used to protect the amino group of the N-terminal residue in…

A: N- terminal residue of peptide has N site , N has lone pair of electrons, thus it can act as…

Q: is/are commonly used to cleave peptide bonds in polypeptides. O dansyl chloride O sodium dodecyl…

A: For the first problem we have to find the organic compound that can be used to cleave peptide bond…

Q: Deduce the sequence of a heptapeptide that contains the amino acids Ala, Arg, Glu, Gly, Leu, Phe,…

A: Amino acid are the organic compounds which contains both amines  and carboxylic acids within the…

Q: Draw out the mechanism for the hydrolysis of the peptide bonds of aspartame. Make sure to include…

A: Here  Two peptide bonds are there in the aspartame which gets cleavage by hydrolysis  The reaction…

Q: Based on the peptide YDCM, which residues are determined via Sanger degradation?

A: A long chain of amino acid is called peptides. These are connected by peptide bonds.

Q: (d) A heptapeptide was found to have an amino acid composition of Asp, Leu, Lys, Met, Phe and Tyr.…

A: The question is based on the concept of biomolecules. we have been given different peptide…

Q: A normal polypeptide and a mutant of the polypeptide were hydrolyzed by an endopeptidase under the…

A: To find kind of amino acid substitution:

Q: draw the primary structure of the peptide DKMMS at pH 7.4 and name this peptide and what chain…

A: Primary structure of a peptide refers to the amino acid sequence in the peptide.

Q: Deduce the sequence of a heptapeptide that contains the amino acids Ala, Arg, Glu, Gly, Leu, Phe,…

A: The Edman degradation of heptapeptide cleaves amino acid Leu and carboxypeptidase form amino acid…

Q: Which of the following C-terminal peptide bonds is more readily cleaved by carboxypeptidase A?…

A: Carboxypeptidase A enzyme is a proteolytic enzyme (exopeptidase) that attacks the peptide bond at…

Q: Suppose that peptide N and O are segments in the globular protein's primary structure, where will…

A: Proteins are made up of amino acid chains.  The bond between the amino acid sequence is called as…

Q: Draw a mechanism for the hydrolysis of the peptide bond in aspartame. Show arrow pushing

A:

Q: Draw out the peptide IYV and clearly label/identify all the Phi, Psi, and peptide bonds present in…

A:

Q: Arginine and lysine side chains fit into trypsin’s binding pocket . One of these side chains forms a…

A:

Q: Which

A: We have to choose Correct option

Q: What is the advantage of using automated peptide synthesis? A) No side products are formed. B) Ease…

A: Automated peptide synthesis is a fast and easy to synthesize many peptides simultaneuosly. It…

Q: Consider the partial sequence of a peptide. I L W A N R M S H V L F A V E A Select all amino acid…

A:

Q: Answer only In base solution, an amino acid is in acid solution, an amino acid is and exists…

A: Amino acids are compounds which contain both an amino group and an acidic group. Alpha amino acids…

Q: In a paragraph form, provide the experimental procedures in the chemical synthesis of protein that…

A: Experimental procedures in the chemical synthesis of protein that contain native serine residues by…

Q: -NH 'N- H,N. NH HN HN `Ph HO, HN. HN" H2N -Ph: Phenyl group, -C6H5 `NH

A:

Q: peptide

A:

Q: A sample of an unknown peptide was divided into two aliquots. One aliquot was treated with trypsin;…

A: To get the sequence of original peptide, we arrange the given fragments one above another according…

Q: shows the specificity pockets. The S₁ pocket has a glutamic acid in the bottom, the S₂ pocket is…

A:

Q: which

A: There is no amino acid which you are asking

Q: Deduce the sequence of a pentapeptide that contains the amino acids Ala, Glu, Gly, Ser, and Tyr,…

A: The amino acids are always formed from N-terminal to C-terminal. The partial hydrolysis of the given…

Q: A protein is a large polypeptide. Polypeptides are polymers of amino acids joined together through a…

A: Concept:  polypeptide bond is nothing but the amide linkage.

Q: НО CH3 HOʻ NH NH NH H3N `NH `NH ČH3 H3C CH3 NH2

A:

Q: Allosteric proteins a) contain distinct regulatory sites and have multiple functional sites. b)…

A: e) All of the above.

Q: -H

A:

Q: Give a curved arrow mechanism for the hydrolysis of the dipeptide under an acidic condition. H20 H*…

A: In this question, we want to give a curved arrow mechanism.  How we can give mechanism for this, you…

Q: Draw this peptide showing correct stereochemistry (hashed/wedged bonds) and please explain…

A:

Q: In the following MSMS af the precursor lon corresponding to the peptide AFDEK, name the b/y lon that…

A: We need to consider the fragment EK.

Q: what is DNFB used in? O peptide synthesis as a protecting group O Sanger degradation as a residue…

A: Give  DNFB

Q: Decide if the side chains of the following peptides are nonpolar or polar, and label the hydrophobic…

A: Non-polar amino acids are hydrophobic in nature and polar amino acids are hydrophilic in nature. (a)…

Q: 2. Draw the complete mechanism using arrows showing the movement of electrons for HIV Protease…

A:

Q: During base excision repair, DNA glycosylase cleaves theN-glycosidic link between the altered base…

A: DNA glycosylase are a family of enzymes which recognize and remove altered or damaged bases from DNA…

Q: Which interaction(s) is/are involved in the primary structure of a protein (choose all that apply)?…

A: We know that primary structure of protein is the linear sequence of amino acids in a peptide or…

Q: Which features are present in the DNA-binding protein represented by 1YSA, which is referred to as a…

A: ✓Following features are present in the DNA-binding Protein represented by 1YSA which is refferred to…

Q: A tetrapeptide is given as: Ser-Lys-Ala-Phe. Which statement is true? a. The listing should be in…

A:

Q: 1.Serine protease is one of the most studied mechanisms in biochemistry. A. Using the diagram…

A: The main player in the catalytic mechanism in the serine proteases is the catalytic triad. The triad…

Q: What is the role of the histidine in the serine protease mechanism? It is a nucleophile. It attaches…

A: In the serine protease mechanism, Given options, Histidine is a nucleophile. Histidine attaches to…

Q: Suggest a reasonable strategy for the synthesis of the dipeptide Leu-Phe, using established protocol…

A: The biomolecules which have carboxylic and amine group containing monomer units are known as…