Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781259709227
Author: Marjorie Kelly Cowan Professor, Heidi Smith
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 13.5, Problem 16AYP
Diagram the steps in B-cell activation, including all types of cells produced.
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Outline the process of B-cell activation against a T-dependent antigen.
Compare and contrast the first and second checkpoint in B cell development (Include terms: Heavy & light chain, surrogate light chain, cell signaling, apoptosis).
describe the process of B-cell activation after a pathogen was recognized and bound to the B-cell receptor?
Chapter 13 Solutions
Microbiology Fundamentals: A Clinical Approach
Ch. 13.1 - Prob. 1AYPCh. 13.1 - Compare the terms antigen, immunogen, and epitope.Ch. 13.1 - Prob. 3AYPCh. 13.1 - Prob. 4AYPCh. 13.1 - Describe the major histocompatibility complex in...Ch. 13.1 - Prob. 1NPCh. 13.2 - Prob. 6AYPCh. 13.2 - Prob. 7AYPCh. 13.2 - Prob. 8AYPCh. 13.2 - Prob. 9AYP
Ch. 13.2 - Prob. 1MMCh. 13.2 - Prob. 2MMCh. 13.3 - List characteristics of antigens that optimize...Ch. 13.3 - Prob. 11AYPCh. 13.3 - Prob. 12AYPCh. 13.3 - Prob. 2NPCh. 13.4 - Prob. 13AYPCh. 13.4 - Explain how naive T cells become sensitized to an...Ch. 13.4 - Prob. 15AYPCh. 13.5 - Diagram the steps in B-cell activation, including...Ch. 13.5 - Prob. 17AYPCh. 13.5 - Explain the various end results of antibody...Ch. 13.5 - Prob. 19AYPCh. 13.5 - Draw and label a graphwith time on the horizontal...Ch. 13.6 - Prob. 21AYPCh. 13.6 - Discuss the qualities of an effective vaccine.Ch. 13.6 - Name the two major categories of vaccines and then...Ch. 13.6 - Explain the principle of herd immunity and the...Ch. 13.6 - 3. Which characteristic is associated with passive...Ch. 13 - A single bacterium has _______ epitope(s). a. a...Ch. 13 - Prob. 2QCh. 13 - Provide an explanation to refute the following...Ch. 13 - The primary B-cell receptor is a. IgD. b. IgA. c....Ch. 13 - Name three antigen-presenting cells, and what...Ch. 13 - Major histocompatibility molecules are critical...Ch. 13 - In humans, B cells mature in the ___ and T cells...Ch. 13 - Explain how the memory response is the cornerstone...Ch. 13 - Conduct research on clonal deletion and write a...Ch. 13 - Which of the following cells is capable of...Ch. 13 - Is antibody diversity generated at the DNA or RNA...Ch. 13 - In order for gene rearrangement of antigen...Ch. 13 - Prob. 13QCh. 13 - Prob. 14QCh. 13 - Using the details of T-cell activation, suggest a...Ch. 13 - A vaccine that contains parts of viruses is called...Ch. 13 - Explain how herd immunity works to protect the...Ch. 13 - Prob. 18QCh. 13 - Prob. 19QCh. 13 - Chronic lymphocytic leukemia leads to the...Ch. 13 - Prob. 21QCh. 13 - Prob. 1VC
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- Explain the two processes by which B-cells are activated to inactivate an antigen?arrow_forwardCompare and contrast the activation of B cells and ofT cellsarrow_forwardExplain the process of B cell clonal selection (remember to mention the cells originated in this process with their functions).arrow_forward
- Explain the difference between a T-cell-dependent and a T-cellindependentresponse.arrow_forwardIllustrate the B-cell maturation process in response to antigen triggeringarrow_forwardDescribe a mechanism by which an antigen can enter the lymph node and make contact with the B-cell receptor.arrow_forward
- Provide one common feature and two differences between B-cell receptors and PRRs.arrow_forwardExplain each of the ways that the immune system has a mechanism of control in the development and function of B cells. What are the ramifications if these control mechanisms are not in place? What control mechanism do you feel is the most important to the development and function of B cells?arrow_forwardDescribe the process of clonal selection of a B cell and recount the roles of plasma cells and memory cells in humoral immunity.arrow_forward
- Compare B cell receptors and T cell receptors for the following criteria: BCR TCR Tyrosine kinases Adaptors and scaffold proteins Phospholipases and lipid kinases GTPases, serine/threonine kinases and phosphatases Transcription factors, cytoskeletal changes, adhesion, metabolismarrow_forwardDiscuss the processes of B cell sensitization, activation, and differentiation, describe the structure and function of antibodies, and explain the primary and secondary immune responses to antigen exposure.arrow_forwardDescribe the requirements for activation of helper T cells by macrophages. Explain how helper T cells promote the immunological defenses provided by cytotoxic T cells and by B cells.arrow_forward
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