Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 45.3, Problem 1EQ
What is the normal function of the PPAR-δ protein in mice?
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The lac genotypes are as shown below:
P+OcZ-Y+A+// P¯O+Z+Y+A+
(i)
The lac operon consists of three structural genes, lacZ, lacY and lacA. Which
structural genes are involved in lactose metabolism? Explain.
(ii)
Draw and explain how lactose repress the gene expression in lac IS/I- heterozygote.
(iii)
What is the function of the promoter in the bacterial operon?
How does the HAEIII enzyme discriminate between the C-G polymorphism in the TAS2R38 gene?
Discuss in general terms the principle of the regulation of theexpression of the trp gene with attenuation in bacteria.
Chapter 45 Solutions
Biology
Ch. 45.1 - Prob. 1CCCh. 45.2 - Prob. 1CCCh. 45.2 - Prob. 1CSCh. 45.2 - Prob. 2CSCh. 45.3 - What is the normal function of the PPAR- protein...Ch. 45.3 - CoreSKILL What was the hypothesis proposed by...Ch. 45.3 - CoreSKILL Assume that the mean weight of both...Ch. 45 - Prob. 1TYCh. 45 - Prob. 2TYCh. 45 - Prob. 3TY
Ch. 45 - Prob. 4TYCh. 45 - The function of ATP during muscle contraction is...Ch. 45 - The function of Ca2+ in skeletal muscle...Ch. 45 - Stimulation of a muscle fiber by a motor neuron...Ch. 45 - Muscle fibers that have a large number of...Ch. 45 - Which of the following statements about movement...Ch. 45 - Prob. 10TYCh. 45 - Compare the structural and functional features of...Ch. 45 - Describe as many types of animal locomotion as you...Ch. 45 - Prob. 3CQCh. 45 - List and briefly describe the steps in the...Ch. 45 - Discuss the three types of muscle tissues found in...
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- A pharmaceutical company developed a drug, CP788, that inhibits the interaction of Grb2 with SH2 domains as a treatment for breast cancer. As the data below shows, the compound inhibits activation of RAS in MDA-MB-468 breast cancer cells (Figure A) and anchorage-dependent growth (Figure B solid line) in MDA-MB-468 breast cancer cells. Note that these experimets were done in the presence of EGF. Briefly explain the steps in the pathway by which inhibition of Grb2/SH2 interaction would inhibit activation of RAS (limit 5-6 sentences). A Inhibition of RAS Activation by CP788 % RAS Activation 120 100 80 60 20 0 0 50 [CP788] UM 100 B Colonies number (% of untreated control) 120 100 80 60 40 20 0 10-² HigHt 10-¹ 10⁰ 10¹ 10² 10³ [CP788] UMarrow_forwardWhat are the major factors in the various mutants of the spike protein?arrow_forwardFor the lac genotypes shown in the following table, predict whether the structural genes (Z) are constitutive, permanently repressed, or inducible in the presence of lactose. Genotype Constitutive Repressed Inducible I+O+Z+ * I-O+Z+ I-OCZ+ I-OCZ+/F=O+ I+OCZ+/F=O+ ISO+Z+ ISO+Z+/F=I+arrow_forward
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