6. Vampire bats are mammals that consume blood as their only source of nutrients. Because blood is rich in iron, it is necessary for the digestive system of the vampire bat to manage excess iron. Like humans, ferritin and transferrin receptor gene products are expressed by the vampire bat genome and function to maintain iron homeostasis. Ferritin A. The iron response element (IRE) binding protein is able to regulate expression of both ferritin and transferrin receptor genes. What feature of these genes allows for specific regulation by the IRE binding protein? B. How is activity of the IRE binding protein regulated? C. In an environment with excess iron, what levels of mRNA and protein do you expect to detect of Ferritin and Transferrin receptor? Briefly explain. Explanation Transferrin receptor RNA levels ( ) high ( ) low ( ) high ( ) low Protein levels () high levels ( ) low levels () high levels ( ) low levels

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter37: The Endocrine System
Section: Chapter Questions
Problem 1VCQ: Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In...
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6. Vampire bats are mammals that consume blood as their only source of nutrients. Because blood
is rich in iron, it is necessary for the digestive system of the vampire bat to manage excess iron.
Like humans, ferritin and transferrin receptor gene products are expressed by the vampire bat
genome and function to maintain iron homeostasis.
Ferritin
A. The iron response element (IRE) binding protein is able to regulate expression of both
ferritin and transferrin receptor genes. What feature of these genes allows for specific
regulation by the IRE binding protein?
B. How is activity of the IRE binding protein regulated?
C. In an environment with excess iron, what levels of mRNA and protein do you expect to
detect of Ferritin and Transferrin receptor? Briefly explain.
Explanation
Transferrin
receptor
RNA levels
( ) high
( ) low
( ) high
( ) low
Protein levels
() high levels
( ) low levels
() high levels
( ) low levels
Transcribed Image Text:6. Vampire bats are mammals that consume blood as their only source of nutrients. Because blood is rich in iron, it is necessary for the digestive system of the vampire bat to manage excess iron. Like humans, ferritin and transferrin receptor gene products are expressed by the vampire bat genome and function to maintain iron homeostasis. Ferritin A. The iron response element (IRE) binding protein is able to regulate expression of both ferritin and transferrin receptor genes. What feature of these genes allows for specific regulation by the IRE binding protein? B. How is activity of the IRE binding protein regulated? C. In an environment with excess iron, what levels of mRNA and protein do you expect to detect of Ferritin and Transferrin receptor? Briefly explain. Explanation Transferrin receptor RNA levels ( ) high ( ) low ( ) high ( ) low Protein levels () high levels ( ) low levels () high levels ( ) low levels
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