a. Explain how you could use worms transformedwith myo-2::GFP to find mutations that disrupt thestructure of the pharynx. How would the presenceof the transgene facilitate the mutant screen?b. Nematodes homozygous for loss-of-function mutations in a gene called pha-4 have no detectablepharyngeal structures. How could you use myo2::GFP to determine if pha-4 is a master regulatory gene that directs development of the pharynxin a manner similar to the way Pax-6/eyeless controls eye development?
a. Explain how you could use worms transformedwith myo-2::GFP to find mutations that disrupt thestructure of the pharynx. How would the presenceof the transgene facilitate the mutant screen?b. Nematodes homozygous for loss-of-function mutations in a gene called pha-4 have no detectablepharyngeal structures. How could you use myo2::GFP to determine if pha-4 is a master regulatory gene that directs development of the pharynxin a manner similar to the way Pax-6/eyeless controls eye development?
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 4.2P
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a. Explain how you could use worms transformed
with myo-2::GFP to find mutations that disrupt the
structure of the pharynx. How would the presence
of the transgene facilitate the mutant screen?
b. Nematodes homozygous for loss-of-function mutations in a gene called pha-4 have no detectable
pharyngeal structures. How could you use myo2::GFP to determine if pha-4 is a master regulatory gene that directs development of the pharynx
in a manner similar to the way Pax-6/eyeless controls eye development?
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