Provide a short answer for each of the questions below. For individuals homozygous for the Duffy gene mutation, which increases resistance to malaria, answer the following questions: 1)What impact do you expect the GATA → GACA mutation will have on the level of Duffy protein expression in red blood cells? 2)What impact do you expect the GATA → GACA mutation will have on the level of Duffy protein expression in endothelial and Purkinje (brain) cells? 3)Explain how this mutation leads to the level of Duffy expression you expect in the different cell types.
Provide a short answer for each of the questions below. For individuals homozygous for the Duffy gene mutation, which increases resistance to malaria, answer the following questions: 1)What impact do you expect the GATA → GACA mutation will have on the level of Duffy protein expression in red blood cells? 2)What impact do you expect the GATA → GACA mutation will have on the level of Duffy protein expression in endothelial and Purkinje (brain) cells? 3)Explain how this mutation leads to the level of Duffy expression you expect in the different cell types.
Biology Today and Tomorrow without Physiology (MindTap Course List)
5th Edition
ISBN:9781305117396
Author:Cecie Starr, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Christine Evers, Lisa Starr
Chapter10: Biotechnology
Section: Chapter Questions
Problem 2CT
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Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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Provide a short answer for each of the questions below. For individuals homozygous for the Duffy gene mutation, which increases resistance to malaria, answer the following questions:
1)What impact do you expect the GATA → GACA mutation will have on the level of Duffy protein expression in red blood cells?
2)What impact do you expect the GATA → GACA mutation will have on the level of Duffy protein expression in endothelial and Purkinje (brain) cells?
3)Explain how this mutation leads to the level of Duffy expression you expect in the different cell types.
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