solve using hardy Weinberg law/ eqaution C-In humans, the Rh factor genetic information is inherited from our parents, but it isinherited independently of the ABO blood type alleles. In humans, Rh+ individuals havethe Rh antigen on their red blood cells, while Rh- individuals do not. There are two bdifferent alleles for the Rh factor known as Rh+ and rh. Assume that a dominant gene Rhproduces the Rh+ phenotype, and that the recessive rh allele produces the Rh-phenotype. In a population that is in Hardy-Weinberg equilibrium, if 160 out of 200individuals are Rh+, calculate the frequencies of both alleles.Close

p2+2pq+q2=0 p2 = dominant homozygous frequency (AA) 2pq = heterozygous frequency (Aa) q2 =…

C-In humans, the Rh factor genetic information is inherited from our parents, but it is inherited independently of the ABO blood type alleles. In humans, Rh+ individuals have the Rh antigen on their red blood cells, while Rh- individuals do not. There are two different alleles for the Rh factor known as Rh+ and rh. Assume that a dominant gene Rh produces the Rh+ phenotype, and that the recessive rh allele produces the Rh- phenotype. In a population that is in Hardy-Weinberg equilibrium, if 160 out of 200 individuals are Rh+, calculate the frequencies of both alleles. OL

C-In humans, the Rh factor genetic information is inherited from our parents, but it is inherited independently of the ABO blood type alleles. In humans, Rh+ individuals have the Rh antigen on their red blood cells, while Rh- individuals do not. There are two different alleles for the Rh factor known as Rh+ and rh. Assume that a dominant gene Rh produces the Rh+ phenotype, and that the recessive rh allele produces the Rh- phenotype. In a population that is in Hardy-Weinberg equilibrium, if 160 out of 200 individuals are Rh+, calculate the frequencies of both alleles. OL

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter42: The Immune System

Section: Chapter Questions

Problem 19RQ: A potential cause of acquired autoimmunity is ___________ . tissue hypersensitivity molecular...

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Why is it that Rh incompatibility can be a serious problem when anRh-negative mother is carrying an Rh-positive fetus, but ABOincompatibility between mother and fetus is usually no problem?That is, a type A mother can usually safely carry a type B fetus.(Hint: The antibodies produced by an Rh-negative mother againstthe Rh antigen are usually IgG, whereas the antibodies producedagainst the A or B antigens are IgM.) Because the Rh antigenobviously serves no vital function (most humans lack it), why do youthink it hasn’t been completely eliminated during human evolution?
Describe the reason as to why inducing plasma cells to secrete IgG instead of IgE prevents type | hypersensitivity.
MHC polymorphism at individual MHC genes appears to have been strongly selected by evolutionary pressures. In other words, there appears to be selection for maintaining hundreds to thousands of different alleles of each MHC gene in the population. This notion is based on the observation that nucleotide differences between alleles that lead to amino acid substitutions are more frequent than those that are silent substitutions (i.e., not changing the amino acid sequence of the protein). In addition, the positions within the MHC protein where most of the allelic sequence variation occurs are not randomly distributed, but are concentrated in certain regions of the MHC protein. This latter point indicates: That some nucleotide sequences within the MHC genes are hot-spots for mutation That MHC genes are more susceptible to point mutations than to larger nucleotide deletions That MHC allelic polymorphism has been driven by selection for diversity in peptide binding specificity That MHC genes…
Hemolytic disease of new born maternal fetal ABO incompatibility occurs more frequently as a result of which specific mismatch?
It was stated that Rh antigens are so sparsely scattered in the red cell surface that IgG molecules bound to the Rh antigens are too far apart to fix C1q.Therefore, complement-mediated hemolysis cannot be invoked to explain hemolytic disease of the newborn. By what mechanism are the red cells destroyed?
What are ABO blood-group antigens?
Rh D - negative individuals generate an immune response when they are exposed to the Rh-D antigen. However, incompatibility in the ABO blood group system occurs naturally in the presence of exposure to the A or B antigen in the blood from individuals. Why do individuals produce an immune response the first time they encounter the A or B antigen as an adult
Where do you find Major Histocompatibility Complex class I molecules? Group of answer choices on the surface of nucleated body cells on the surface of leukocytes
If a cell cannot make any Rb protein, how will this affect the function of E2F?
In terms of antigens and antibodies, explain why O- is considered a universal donor and why AB+ is considered a universal recipient. Even so, why can’t whole blood O- be donated to a person of type AB+ blood?
Surprisingly, humans as well as mice deficient in the complement protein, C3, have greatly reduced antibody responses to T cell-dependent antigens, and are impaired in their ability to control HSV infections. When C3-deficient mice are infected with HSV, once at day 0 and then a second time 4 weeks later, their antibody response is altered compared to wild-type mice, as shown in the figure #3 below. a) What is a likely explanation for the altered antibody response in the absence of complement C3? For fugure #4: For this experiment, mice are infected with varying doses of the HSV-rd virus, and peak IgG responses to the viral surface glycoproteins are measured. The results are shown in the fugure #4. b) What is the most likely explanation for these data? Do these results impact your answer to the part above (a)? Explain your reasoning.
8) In addition to the ABO self-antigen system, another red blood cell self-antigen system is the Rh factor. The gene for this self=antigen system exhibits complete dominance with Rh positive (the presence of self-antigen Rh) being completely dominant over Rh negative (the absence of the self-antigen Rh). Rh positive is symbolized as + and Rh negative is symbolized as -. a. Geraldo has B- blood and Arline has O+ blood. Geraldo’s father has B+ blood and his mother has O- blood. Arline’s mother has O= blood and her father has A+ blood. Geraldo and Arline have a daughter, Elise. Using a Punnett square, what are the possible blood types for Elise? b. What is Geraldo’s genotype? c. What is Arline’s genotype?